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Letrozole

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Formula: C17H11N5
CAS: 112809-51-5
search Element: letrozole

Identification

Structural Formula
Letrozole
CAS:
112809-51-5
EINECS:
Molecular Formula:
C17H11N5
MDL:
MFCD00866241
SMILES:
C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3
Synonym:
letroz ; cgs-20267 ; lelrozol ; femara ; lerozole ; letrozole ; letrozolex ; letrozole99% ; letrazole ; letrozol


Description

Letrozole acts as a nonsteroidal CYP19 (aromatase) inhibitor. It is also known to inhibit estradiol production in vitro in hamster ovarian tissue that is LH-stimulated. Letrozole has not been shown to have a significant effect on progesterone production up to 350 M. Letrazole has been shown to inhibit aldosterone production in vitro in rat adrenal tissue stimulated by ACTH. No significant effect has been seen on corticosterone production at 350 M. Letrozole has no effect on corticosterone or aldoterone levels in vivo in ACTH-treated rats.


Suppliers

Autech Industry Co.,Limited
AIC243972
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6212484
Shandong Minglang Chemical Co., Ltd
SMC3151260
H&Z Industry Co.,Ltd
HIC180720
Wuhan PharmChem Co., LTD.
WP225675
Aea.ltd
A63126
Shandong SanYoung Industry Co., Ltd
SSI3151260
Chemlyte Solutions
CS162486
Arcadia Biotechnology
AB189567
Shanghai Worldyang Chemical Co., Ltd.
SWC3331332
Sancai Industry Co.,Ltd.
SIC216864
Daming Changda Co., Ltd.
LLB00232
Hangzhou Keying Chem Co., Ltd.
HKC2701080
Hangzhou Lingrui Chemical Co., Ltd.
HLC3151260
Sigma-Aldrich International GmbH
SI288864
scienTEST - bioKEMIX GmbH
S-B225900
Carbone Scientific Co., Ltd.
CS252756
AK Scientific, Inc.
AS171513
Amadis Chemical Company Limited
ACCL2791395
Leap Chem Co., Ltd
LC162486
Santa Cruz Biotechnology, Inc.
204791
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SC168504
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AD184552
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NXB208832
4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-benzonitrile
Hangzhou J&H Chemical Co., Ltd.
HJC821532860
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Angene International Limited
AGN-PC-04XZ2M
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Manchester Organics Limited
U35944

Prices & Availability




Data is processed


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Properties for Letrozole

Molecular Weight:
285.3 g·mol−1
Density:
~1.2 g/cm3 (Predicted)
Melting point:
181-183 °C
Boiling point:
~563.5° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (<1 mg/ml at 25° C), DMSO (57 mg/ml at 25° C), ethanol (<5 mg/ml, partially ), chloroform, and methanol.
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Safety & Transport Information

Risk Codes:
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Letrozole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Wuxi Mizat Chemical Technology Co., Ltd. | Share Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | TCS INDUSTRY LTD. | Lanospharma Laboratories Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Xiang Ding Chemical International Co., Ltd | New Dragon Industrial Co., Ltd | Zhejiang Xianju Greeleaf Pharmaceutical Factory | Watson International Ltd | 3B Scientific Corporation | Shanxi Jinjin Chemical Co., Ltd. | Aryl S.A. | Auspure Biotechnology Co., Ltd. | Suzhou Highfine Biotech Co.,Ltd. | CCS. CHEM. Co., Ltd. | Jinan Jinao Chemical Development Co., Ltd. | Heta Pharm & Chem Co., Ltd. | scienTEST | Pharmasi Chemicals Co., Ltd. | Hangzhou Hysen Pharma Co., Ltd. | Afine Chemicals Limited | Shanghai PI Chemicals Ltd. | Qichun QiLong Chemical Co., Ltd. | Taizhou Creating Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Vesino Industrial Co., Ltd. | Jiangsu Honghui Pharmaceutical Co., Ltd. | Taizhou Huading Chemical Co., Ltd. | Duheng Bio-tech Co., Ltd. | Beijing Ribio Biotech Co., Ltd. | Zhejiang Esun Chemical Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Clearsynth Canada INC. | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai Yingxuan Chempharm Co., Ltd. | Shanghai AOKChem Group Limited | B.M. Import & Export Ltd. | Zibo Panxin Pharmaceutical Co., Ltd. | Unispec Chemicals Co. | Genatal Life Science Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Hangzhou Sida Organic Chemical Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Haihang Industry Co., Ltd. | Ningbo Haishu Hobid Imp & Exp Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Bichem Lab Co., Ltd. | ShangHai Biochempartner Co., Ltd. | Hangzhou Holypharm Biotech Co., Ltd. | Suzhou Bichal Biological Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Benro Internatinal Co., Linc | API Vanguard | Jinan Aery Pharmaceutical Co,.Ltd. | Zhuhai Jiacheng Bio-Tech Co., Ltd. | Guangzhou Kafen Biotech Co.,Ltd

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