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Lapatinib ditosylate

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Formula: C29H26ClFN4O4S . 2(C7H8O3S)
CAS: 388082-78-8

Identification

Structural Formula
Lapatinib ditosylate
CAS:
388082-78-8
EINECS:
Molecular Formula:
C29H26ClFN4O4S . 2(C7H8O3S)
MDL:
MFCD09264195
SMILES:
CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
Synonym:
lapatinib ditosylate monohydrate ; xyene sulfonate lapatinib ; lapatinib(gw572016) ; n-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)-quinazolin-4-ylamine ditosylate hydrate ; lapatinib, tykerb, gw572016 ; lapatinib ditosylate hydrate ; lapatinib ditosylate ; lapatinb ; lapatinib ditosilate ; lapatinib ditosylate (gw-572016)


Description

Lapatinib Ditosylate is a selective and effective inhibitor of ErbB-2 and EGFR dual tyrosine kinases. ErbB-2 and EGFR dual tyrosine kinases are growth promoting factors that are over expressed in some breast cancer cell lines. Research studies have reported that Lapatinib Ditosylate can inhibit breast cancer cell proliferation.


Suppliers

Autech Industry Co.,Limited
AIC10804320
Ambeed, Inc.
A208985
H&Z Industry Co.,Ltd
HIC8003200
FUDI Chemical Co. Ltd.
FCC8803520
Shandong SanYoung Industry Co., Ltd
SSI14005600
Xiamen Equation Chemical Co.,Ltd
XECC12806400
Shanghai UCHEM Inc.
UCHEM-6440
Zouping Mingxing Chemical Co., Ltd.
ZMC14005600
CSNpharm, Inc.
CSN11269
Hangzhou Keying Chem Co., Ltd.
HKC12004800
Hangzhou Lingrui Chemical Co., Ltd.
HLC14005600
Hefei Hirisun Pharmatech Co., Ltd
HR130405
CM Fine Chemicals
CFC6802720
CM Fine Chemicals
CFC6802720
Simagchem Corporation
SC8402520
Xingrui Industry Co., Limited
XIL11604640
Capot Chemical Co., Ltd.
7684
Leap Chem Co., Ltd
LC7202160
Santa Cruz Biotechnology, Inc.
202205
Dayang Chem (Hangzhou) Co.,Ltd.
DC12404960
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CAS equal suppliers

Lapatinib ditosylate hydrate
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC113489
Lapatinib ditosylate hydrate
Ambeed, Inc.
A447246
Lapatinib Ditosylate Hydrate
CSNpharm, Inc.
CSN12862
Lapatinib ditosylate 1-hydrate
AK Scientific, Inc.
AS17105130
Lapatinib ditosylate 1-hydrate
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI621024840
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Arcadia Biotechnology
AB18905670
Lapatinib ditosylate 1-hydrate
Chemlyte Solutions
CS16204860
Lapatinib ditosylate monohydrate
Hefei Hirisun Pharmatech Co., Ltd
HR130406
Lapatinib ditosylate monohydrate
Hangzhou Lingrui Chemical Co., Ltd.
HLC336013440
Lapatinib Ditosylate Hydrate; GW-572016;
Excenen Pharmatech Co., Ltd.
EX-A2821
N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine bis(4-methylbenzenesulfonate)
Gihi Chemicals Co., Limited
GCL81540326160
N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate) hydrate
BLD Pharmatech Ltd
BP58590175770

Prices & Availability




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Properties for Lapatinib ditosylate

Molecular Weight:
925.46 g·mol−1
Melting point:
241-252° C
Boiling point:
750.7° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (200 mg/ml), water (1-10 µM), Buffers, ethanol (<1 mg/ml at 25° C), and other additives may increase or decrease the aqueous solubility.
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Safety & Transport Information

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Alternative Distributors of [Lapatinib ditosylate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

YHEDC (Yi Heng Enterprises Development Co.) | Yore Chemipharm Co., Limited | East Chemical Industry Co., Ltd. | Qichun QiLong Chemical Co., Ltd. | Melone Pharmaceutical Co., Ltd. | Nanjing Ange Pharmaceutical Co., Ltd. | Zhejiang Esun Chemical Co., Ltd. | ShangHai Biochempartner Co., Ltd. | ZhiYu Biotechnology Co., Ltd. | Shanghai Yongyi Biotechnology Co., Ltd. | Shanghai Yingxuan Chempharm Co., Ltd. | Shanghai AOKChem Group Limited | Suzhou Rovathin Pharmatech Co., Ltd | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Bepharm Ltd. | Shanghai Marketing Center of Yangzhou Princechem Co., Ltd. | Apichem Chemical Technology Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Wuhan Sunrise Technology Development Company Ltd. | Rosewell Industry Co., Ltd. | Jinan Great Chemical Co., Ltd. | Acopin Industrial Limited | Bichem Lab Co., Ltd. | Zouping Mingxing Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Watson International Ltd | Pharmfar Co., Ltd. | Aopharm | BOC Sciences | Skyrun Industrial Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Gihi Chemicals Co., Limited

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