Lansoprazole | CAS 103577-45-3 | Chemical-Suppliers

Element: lansoprazole

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C-S » Chemicals » lansoprazole-PX966374

Identification

Lansoprazole

CAS:

103577-45-3

EINECS:

Molecular Formula:

C₁₆H₁₄F₃N₃O₂S

MDL:

MFCD00866873

SMILES:

CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F

Synonym:

cinfa ; lanzor ; promp ; lanz ; lanso ; alter ; ulpax ; zoton ; davur ; ogast

Description

Lansoprazole is a ATP4A (H⁺,K⁺-ATPase) inhibitor (IC₅₀ = 6.3 μM) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC₅₀ = 0.09 µM for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro. Also blocks swelling-dependent chloride channel (ICI swell) in NIH3T3 fibroblasts. Lansoprazole is more potent than omeprazole.

Suppliers

Chemlyte Solutions

CS216648

Autech Industry Co.,Limited

AIC3241296

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI8283312

Shandong Minglang Chemical Co., Ltd

SMC4201680

H&Z Industry Co.,Ltd

HIC240960

Shandong SanYoung Industry Co., Ltd

SSI4201680

Nantong Xindao Biotech Ltd

NXB3121248

Recordati S.P.A.

RS192576

CellMark AB

CA132396

CSNpharm, Inc.

CSN16685

Hangzhou Keying Chem Co., Ltd.

HKC3601440

Sigma-Aldrich International GmbH

SI3841152

scienTEST - bioKEMIX GmbH

S-B3001200

Finetech Industry Limited

FIL3001200

Hefei Hirisun Pharmatech Co., Ltd

HR131132

CM Fine Chemicals

CFC204816

AK Scientific, Inc.

AS228684

Xingrui Industry Co., Limited

XIL3481392

Leap Chem Co., Ltd

LC216648

Santa Cruz Biotechnology, Inc.

203101

Dayang Chem (Hangzhou) Co.,Ltd.

DC3721488

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CAS equal suppliers

Lansoprazole, 98+%

Alfa (A Johnson Matthey Company)

A5761728

1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-

Hangzhou J&H Chemical Co., Ltd.

HJC2427397092

2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole

BLD Pharmatech Ltd

BP1922457672

Prices & Availability

Data is processed

Properties for Lansoprazole

Molecular Weight:

369.36 g·mol−1

Density:

1.50 g/cm³ (Predicted)

Melting point:

178-182 °C dec.

Boiling point:

555.79° C at 760 mmHg (Predicted)

Solubility:

Soluble in methanol, ethanol (14 mg/ml at 25° C), DMF (~30 mg/ml), and DMSO (74 mg/ml at 25° C). Insoluble in water.

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

2-8°C

Alternative Distributors of [Lansoprazole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified