Lamotrigine | CAS 84057-84-1 | Chemical-Suppliers

Element: lamotrigine

Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » lamotrigine-PX79302

Identification

Lamotrigine

CAS:

84057-84-1

EINECS:

281-901-8

Molecular Formula:

C₉H₇Cl₂N₅

MDL:

MFCD00865333

SMILES:

C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N

Synonym:

bw-430c ; lemotrigine ; lamotrigin ; gi 267119x ; lamictal ; lamotrigine ; lamotringine ; lamotrigine api ; ltg ; bw-430

Description

Lamotrigine is a phenyltriazine sodium channel protein inhibitor of presynaptic neurons. Studies indicate that Lamotrigine blocked sustained repetitive firing of neurons in a dose dependent manner in cultured mouse spinal cords. These studies indicate that Lamotrigine is effective at suppressing the release of glutamate and aspartate, but have no effect on acetylcholine and GABA release. Lamotrigine is inactivated by liver microsomes, via hepatic glucuronidation. It is believed that Lamotrigine modulates the fast voltage-dependent sodium currents in a manner similar to phenytoin and carbamazepine. Futhermore, Lamotrigine displays a small frequency dependent inhibition of depolarized potentials that result from sodium currents. Lamotrigine is an inhibitor of Serotonin.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI7593036

Autech Industry Co.,Limited

AIC2971188

Shandong SanYoung Industry Co., Ltd

SSI3851540

Chemlyte Solutions

CS198594

Tessenderlo Chemie

TC198594

Suan Farma, Inc

SFI165660

IBIS Chemie International

ICI2751100

Hainan Zhongxin Chemical Co., Ltd.

HZC3741496

Aecochem Corp.

AC154462

CSNpharm, Inc.

CSN12998

Hangzhou Lingrui Chemical Co., Ltd.

HLC3851540

Sigma-Aldrich International GmbH

SI3521056

scienTEST - bioKEMIX GmbH

S-B2751100

Finetech Industry Limited

FIL2751100

Carbone Scientific Co., Ltd.

CS308924

Hefei Hirisun Pharmatech Co., Ltd

HR011104

CM Fine Chemicals

CFC187748

AK Scientific, Inc.

AS209627

Xingrui Industry Co., Limited

XIL3191276

BOC Sciences

BS132396

Leap Chem Co., Ltd

LC198594

Santa Cruz Biotechnology, Inc.

201079

Dayang Chem (Hangzhou) Co.,Ltd.

DC3411364

Get Quick Quote

CAS equal suppliers

6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine

Manchester Organics Limited

X24906

6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine

BLD Pharmatech Ltd

BP441013230

1,2,4-Triazine-3,5-diamine, 6-(2,3-dichlorophenyl)-

Angene International Limited

AGN-PC-04XSOH

Prices & Availability

Data is processed

Properties for Lamotrigine

Molecular Weight:

256.09 g·mol−1

Density:

1.57 g/cm³ (Predicted)

Melting point:

177-181°C

Boiling point:

503.10° C at 760 mmHg (Predicted)

Solubility:

DMSO: 20 mg/mL at 60 °C, soluble

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

6.1(b)

Hazard Symbols:

T, Xi, F

Storage temperature :

2-8°C

RID/ADR certification :

UN 2811 6.1 / PG 3

Alternative Distributors of [Lamotrigine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified