Ketotifen fumarate | CAS 34580-14-8

Element: ketotifen fumarate

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C-S » Chemicals » ketotifen-fumarate-PX81800

Identification

Ketotifen fumarate

CAS:

34580-14-8

EINECS:

252-100-0

Molecular Formula:

C₂₃H₂₃NO₅S

MDL:

MFCD00079394

SMILES:

CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=C/C(=O)O)C(=O)O

Synonym:

(2e)-but-2-endis?ure--4-(1-methylpiperidin-4-yliden)-4,9-dihydro-10h-benzo[4,5]cyclohepta[1,2-b]thiophen-10-on(1:1) ; 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10h-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (2e)-but-2-enedioate (1:1) ; ketotifen fumarate ; 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10h-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (2e)-but-2-enedioate ; anatifen ; zaditen ; ketotifene fumarate ; allerkif ; zaditor ; hc20-511fumarate ; ketotifen fumarat ; totifen ; zasten

Description

Ketotifen fumarate, a Histamine H1 receptor antagonist, has been noted to inhibit histamine release from lymphocytes and monocytes at 0.1-10 μM. Ketotifen has demonstrated inhibiting characteristics against mast cell growth, therefore reducing myofibroblast hyperplasia. This compound has displayed induction capacities in primary necrosis of interleukin-5-treated eosinophils. Ketotifen fumarate is an inhibitor of PDE.

Suppliers

H&Z Industry Co.,Ltd

HIC7202880

Shandong SanYoung Industry Co., Ltd

SSI12605040

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI24849936

Indofine Chemical Co, Inc.

Bio-851

Qingdao Hong Jin Chemical Co., Ltd.

QHJC12606300

Shanghai Worldyang Chemical Co., Ltd.

SWC13325328

Xiamen Equation Chemical Co.,Ltd

XECC11525760

Sancai Industry Co.,Ltd.

SIC8643456

Aecochem Corp.

AC5041512

CSNpharm, Inc.

CSN19403

Hangzhou Lingrui Chemical Co., Ltd.

HLC12605040

scienTEST - bioKEMIX GmbH

S-B9003600

Carbone Scientific Co., Ltd.

CS10083024

AK Scientific, Inc.

AS6842052

Simagchem Corporation

SC7562268

Xingrui Industry Co., Limited

XIL10444176

BOC Sciences

BS4321296

Leap Chem Co., Ltd

LC6481944

Santa Cruz Biotechnology, Inc.

201094

Dayang Chem (Hangzhou) Co.,Ltd.

DC11164464

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CAS equal suppliers

4-(1-Methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one

Manchester Organics Limited

N25940

4-(1-Methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9H)-one fumarate

BLD Pharmatech Ltd

BP1782053460

Prices & Availability

Data is processed

Properties for Ketotifen fumarate

Molecular Weight:

425.53 g·mol−1

Melting point:

192 C

Boiling point:

488.9 °C at 760 mmHg

Flash point:

249.5 °C

Solubility:

Soluble in water (10 mg/ml), DMSO (100 mM), and methanol.

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

Xn, T

Storage temperature :

Store at RT

Alternative Distributors of [Ketotifen fumarate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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