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Ketoconazole(Cis-1-Acetyl-4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Yl-Methyl)-1,3-Dioxolane-4-Yl]Methoxyl]Phenyl]Piperazine)

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Formula: C26H28Cl2N4O4
CAS: 65277-42-1

Identification

Structural Formula
Ketoconazole(Cis-1-Acetyl-4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Yl-Methyl)-1,3-Dioxolane-4-Yl]Methoxyl]Phenyl]Piperazine)
CAS:
65277-42-1
EINECS:
265-667-4
Molecular Formula:
C26H28Cl2N4O4
MDL:
MFCD00058579
Synonym:
onofin k ; nizral ; fungoral ; nizoral ; fungarest ; kw-1414 ; brizoral ; r-41400 ; fitonal ; ketoderm




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Prices & Availability




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Properties for Ketoconazole(Cis-1-Acetyl-4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Yl-Methyl)-1,3-Dioxolane-4-Yl]Methoxyl]Phenyl]Piperazine)

Molecular Weight:
531.43 g·mol−1
Density:
~1.4 g/cm3 (Predicted)
Melting point:
146°C
Boiling point:
~753.4° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (20 mg/mL warm), ethanol (20 mg/mL warm), chloroform, water (<1 mg/mL), and methanol.
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2
GHS09

GHS09
Environmental hazard
  • Acute hazards to the aquatic environment, category 1
  • Chronic hazards to the aquatic environment, categories 1, 2
  • Environmental toxicity, categories 1, 2

Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R48/22 - Harmful: danger of serious damage to health by prolonged exposure if swallowed
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R60 - May impair fertility
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
S60 - This material and its container must be disposed of as hazardous waste
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
S7 - Keep container tightly closed
Hazard Classes:
6.1(b)
Hazard Symbols:
T, N, F
Hazard symbol T Hazard symbol N Hazard symbol F
Storage temperature :
2-8°C
RID/ADR certification :
UN 2811 6.1 / PG 3
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Alternative Distributors of [Ketoconazole(Cis-1-Acetyl-4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-Imidazol-1-Yl-Methyl)-1,3-Dioxolane-4-Yl]Methoxyl]Phenyl]Piperazine)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Inter-Chemical Ltd. | Santec Chemicals Corp. | Ningbo Zhengrun Chemicals Co., Ltd. Exp. Dept. | Hallochem Pharma Co., Ltd. | Argosi International Co., Ltd. | 3B Scientific Corporation | Shanghai Eagle Chemical Co., Ltd. | Hangzhou Think Chemical Co., Ltd. | Molekula GmbH | Hangzhou Cowin Pharma Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | East Chemical Industry Co., Ltd. | TCI Europe NV | Golden Harvest Fine Chemical Co., Ltd. | Changzhou An-Yuan Imp. & Exp. Corporation | New Dragon Industrial Co., Ltd | Zibo Panxin Pharmaceutical Co., Ltd. | Discovery Fine Chemicals Limited | Unispec Chemicals Co. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Suzhou Rovathin Pharmatech Co., Ltd | All Right Chemical Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Ningbo Hi-Tech Biochemicals Co., Ltd. | Hubei MaxSource Chem Co., Ltd. | King Tang Chemical Group Industry Co., Ltd. | Watson International Ltd | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Xiamen Hisunny Chemical Co., Ltd. | scienTEST | Gihi Chemicals Co., Limited | Clearsynth Canada INC. | Nebula Chemicals Co, Ltd. | Haihang Industry Co., Ltd.

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