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Josamycin

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Formula: C42H69NO15
CAS: 16846-24-5
search Element: josamycin
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Identification

Structural Formula
Josamycin
CAS:
16846-24-5
EINECS:
240-871-6
Molecular Formula:
C42H69NO15
MDL:
MFCD00211043
SMILES:
C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)OC(=O)C)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O)C)O
Synonym:
iosalide ; josamina ; yl-704a3 ; en 141 ; josacine ; wilprafen ; c12662 ; vilprafen ; josamycin ; jomybel


Description

Josamycin is a member of the leucomycin group of macrolide antibiotics with a 16 member lactone ring produced by Streptomyces kitasatoensis and Streptomyces narbonensis var. josamyceticus. The compounds main use has been against gram-positive bacteria. The compound has been documented to function through direct inhibition of peptidyltransferase reaction as well as drop off of peptidyl-tRNA translation from ribosomes. The strength action was observed to be dependent on peptide length, no more than 3 amino acids, and composition of amino acids, fMet-Phe-tRNA or fMet-Val-tRNA. Kinetic studies demonstrated that Josamycin binds directly to the ribosome.


Suppliers

Autech Industry Co.,Limited
AIC243972
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Shandong Minglang Chemical Co., Ltd
SMC3151260
+
Lori Industry Co., Ltd
LI198594
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Shandong SanYoung Industry Co., Ltd
SSI3151260
+
Sancai Industry Co.,Ltd.
SIC216864
+
Sigma-Aldrich International GmbH
SI288864
+
Carbone Scientific Co., Ltd.
CS252756
+
Zehao Industry Co., Ltd.
ZI216648
+
Leap Chem Co., Ltd
LC162486
+
Santa Cruz Biotechnology, Inc.
351855
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BLD Pharmatech Ltd
BP140400421200

Prices & Availability




Data is processed


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Properties for Josamycin

Molecular Weight:
827.99 g·mol−1
Density:
~1.21 g/cm3 (Predicted)
Melting point:
131.5°C
Boiling point:
~877.79 °C at 760 mmHg (Predicted)
Solubility:
Soluble in water (Partly miscible), acidic water, ethanol, chloroform, acetone, ethyl acetate, dioxane, butanol, ether, carbon tetrachloride, toluene, and benzene.
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Safety & Transport Information

Storage temperature :
2-8°C
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Alternative Distributors of [Josamycin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Discovery Fine Chemicals Limited | East Chemical Industry Co., Ltd. | BOC Sciences

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Downloads

Mol File:
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MSDS:
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