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Itraconazole

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Formula: C35H38Cl2N8O4
CAS: 84625-61-6
search Element: itraconazole

Identification

Structural Formula
Itraconazole
CAS:
84625-61-6
EINECS:
Molecular Formula:
C35H38Cl2N8O4
MDL:
MFCD00870168
SMILES:
CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[C@H]5CO[C@](O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl
Synonym:
triasporin ; sporamelt ; sporanox ; itrizole ; sempera ; r51211 ; akos 92112 ; orungal ; canditral ; itraconaz


Description

Itraconazole is a triazole antifungal agent. It inhibits the fungal CYP(cytochrome P450) oxidase-mediated synthesis of ergosterol. Itraconazole also acts as an effective hedgehog signaling inhibitor in a Ptch-independent manner, presumably by binding smoothened (Smo) at a site distinct from that targeted by cyclopamine and SAG. Itraconazole is an inhibitor of CYP3A4.


Suppliers

Autech Industry Co.,Limited
AIC3241296
Krada CPS Industry S.L
KCIS2641320
OPQ Chemical Co., Ltd
OC252756
Ambeed, Inc.
A154189
Nantong Xindao Biotech Ltd
NXB3121248
Chemlyte Solutions
CS216648
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8283312
Shandong Ench Chemical Co.,Ltd
SECC3601800
Lori Industry Co., Ltd
LI264792
Refine Chemical Co.,Ltd.
RCC2881152
H&Z Industry Co.,Ltd
HIC240960
Gyma Laboratories Of America, Inc.
GLOA4082040
Wuhan Atomole Chemicals Co., Ltd.
AT-6475
Hangzhou Cherry Pharmaceutical Technology Co., Ltd.
HCPT6123060
Sancai Industry Co.,Ltd.
SIC2881152
Arakato Development Ltd
AD276828
Aecochem Corp.
AC168504
CSNpharm, Inc.
CSN13003
Hangzhou Keying Chem Co., Ltd.
HKC3601440
Sigma-Aldrich International GmbH
SI3841152
Finetech Industry Limited
FIL3001200
Carbone Scientific Co., Ltd.
CS3361008
Hefei Hirisun Pharmatech Co., Ltd
HR013633
AK Scientific, Inc.
AS228684
Xingrui Industry Co., Limited
XIL3481392
Capot Chemical Co., Ltd.
16053
Zehao Industry Co., Ltd.
ZI288864
BOC Sciences
BS144432
Amadis Chemical Company Limited
ACCL3721860
Leap Chem Co., Ltd
LC216648
Santa Cruz Biotechnology, Inc.
205724
Dayang Chem (Hangzhou) Co.,Ltd.
DC3721488
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CAS equal suppliers

Itraconazole D5
Santa Cruz Biotechnology, Inc.
sc-280871
Itraconazole, 98%
Alfa (A Johnson Matthey Company)
A5441632
Itraconazole Hydrochloride
Medibro Corporation Limited
MCL14045616

Prices & Availability




Data is processed


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Properties for Itraconazole

Molecular Weight:
705.63 g·mol−1
Density:
1.41 g/cm3 (Predicted)
Melting point:
166 °C
Boiling point:
849.98° C at 760 mmHg (Predicted)
Solubility:
chloroform: 50 mg/mL, clear, colorless
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R36/38 - Irritating to eyes and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
Xi, Xn, T, F
Hazard symbol T Hazard symbol F Hazard symbol Xn Hazard symbol Xi
Storage temperature :
2-8°C
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Alternative Distributors of [Itraconazole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Inter-Chemical Ltd. | Shouguang Fukang Pharmaceutical Co., Ltd. | Matrix Laboratories Limited | Sai Ram Organics Private Limited | CCS. CHEM. Co., Ltd. | Argosi International Co., Ltd. | 3B Scientific Corporation | Shanghai Eagle Chemical Co., Ltd. | Ningbo Yuanfang Biochemicals Co., Ltd. | Molekula GmbH | Shanghai Coming Hi-Technology Co., Ltd. | Jinan Decheng Medical Technology Co., Ltd. | Synfine Research Inc. | ChengDu KaiXin Technology Development Co., Ltd. | Discovery Fine Chemicals Limited | Unispec Chemicals Co. | Chengdu Qiaofeng Technological Development Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Suzhou Vosun Chemical Co.,Ltd. | Atomole Scientific Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Hefei Photochem Trading Co., Ltd | Jinan Great Chemical Co., Ltd. | Ningbo Hi-Tech Biochemicals Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | King Tang Chemical Group Industry Co., Ltd. | Watson International Ltd | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | Gihi Chemicals Co., Limited | Haihang Industry Co., Ltd.

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