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3-(4-Isopropylbenzylidenyl)­indolin-2-one

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Formula: C18H17 N O
CAS: 186611-55-2
search Element: isopropylbenzylidenyl indolin
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Identification

Structural Formula
3-(4-Isopropylbenzylidenyl)­indolin-2-one
CAS:
186611-55-2
EINECS:
Molecular Formula:
C18H17 N O
MDL:
MFCD00118155
SMILES:
CC(C)C1=CC=C(C=C1)C=C2C3=CC=CC=C3NC2=O
Synonym:
2h-indol-2-one,1,3-dihydro-3-[[4-(1-methylethyl)phenyl]methylene]- ; 3-(4-isopropylbenzylidenyl)indolin-2-one ; su 4313


Description

3-(4-Isopropylbenzylidenyl)indolin-2-one is a non-selective inhibitor of receptor tyrosine kinases (RTKs). It inhibits PDGFR, FLK-1, EGFR, HER-2, IGF-1R RTKs (IC50 ~5-25μM). 3-(4-Isopropylbenzylidenyl)indolin-2-one consists primarily of the E-isomer; contains ~5% of the Z-isomer.


Suppliers

Santa Cruz Biotechnology, Inc.
202413
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CAS equal suppliers

3-(4-Isopropylbenzylidenyl)indolin-2-one
Santa Cruz Biotechnology, Inc.
sc-202413
3-(4-Isopropylbenzylidenyl)indolin-2-one
Amadis Chemical Company Limited
ACCL496024800

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Properties for 3-(4-Isopropylbenzylidenyl)­indolin-2-one

Molecular Weight:
263.33 g·mol−1
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Alternative Distributors of [3-(4-Isopropylbenzylidenyl)­indolin-2-one]

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