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Irbesartan

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Formula: C25H28N6O
CAS: 138402-11-6
search Element: irbesartan

Identification

Structural Formula
Irbesartan
CAS:
138402-11-6
EINECS:
Molecular Formula:
C25H28N6O
MDL:
MFCD00864464
SMILES:
CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5
Synonym:
avapro ; irbesarta ; aprovel ; bms-186295 ; lrbesartan ; sr-47436 ; irbesartan ; irbesatan ; irbersartan ; irbesartan(avapro)


Description

Irbesartan is a highly potent and selective antagonist of the AT1 (angiotensin II type 1) receptor with an IC50 = 1.3 nM. This compound has no affinity for AT2 receptors. Pretreatment with irbesartan decreases angiotensin II-induced apoptosis in rat vascular smooth muscle cells by blocking angiotensin II internalization in a concentration-dependent manner.


Suppliers

H&Z Industry Co.,Ltd
HIC200800
Shandong SanYoung Industry Co., Ltd
SSI3501400
Aozeal Certified Standards (AOCS), Inc.
I0003.00
Ambeed, Inc.
A262974
Gyma Laboratories Of America, Inc.
GLOA3401700
Guangzhou Topwork Chemical Co., Ltd.
GTC3601440
Arcadia Biotechnology
AB210630
Xiamen Equation Chemical Co.,Ltd
XECC3201600
Aecochem Corp.
AC140420
CSNpharm, Inc.
CSN12537
Hangzhou Lingrui Chemical Co., Ltd.
HLC3501400
Sigma-Aldrich International GmbH
SI320960
scienTEST - bioKEMIX GmbH
S-B2501000
CM Fine Chemicals
CFC170680
AK Scientific, Inc.
AS190570
Xingrui Industry Co., Limited
XIL2901160
Capot Chemical Co., Ltd.
21382
BOC Sciences
BS120360
Leap Chem Co., Ltd
LC180540
Santa Cruz Biotechnology, Inc.
218603
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Prices & Availability




Data is processed


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Properties for Irbesartan

Molecular Weight:
428.53 g·mol−1
Density:
~1.3 g/cm3 (Predicted)
Melting point:
180-181 °C
Boiling point:
~648.6° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (>25 mg/ml), ethanol (~0.5 mg/ml), methanol, DMF (~20 mg/ml), and water (<1 mg/ml at 25° C).
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Irbesartan]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Inter-Chemical Ltd. | Zhejiang Tianyu Pharmaceutical & Chemical Co., Ltd | Anhui Worldbest Import and Export Co., Ltd. | Matrix Laboratories Limited | Molekula GmbH | Hallochem Pharma Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | Hangzhou Think Chemical Co., Ltd. | Zhejiang Jiangbei Pharmaceutical Co., Ltd. | Afine Chemicals Limited | Ningbo Yuanfang Biochemicals Co., Ltd. | Xiang Ding Chemical International Co., Ltd | Qichun QiLong Chemical Co., Ltd. | Zhejiang Materials Industry Chemical Group Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Changzhou An-Yuan Imp. & Exp. Corporation | Synfine Research Inc. | New Dragon Industrial Co., Ltd | Donboo Amino Acid Co., Ltd. | Conier Chem & Pharma Ltd | ShangHai Biochempartner Co., Ltd. | Zibo Panxin Pharmaceutical Co., Ltd. | Discovery Fine Chemicals Limited | Formax Chemicals Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Suzhou Vosun Chemical Co.,Ltd. | Atomole Scientific Co., Ltd. | TCS INDUSTRY LTD. | Suzhou Rovathin Pharmatech Co., Ltd | Hangzhou Pharma & Chem Co. Ltd. | Lanospharma Laboratories Co., Ltd. | Jinan Great Chemical Co., Ltd. | Bepharm Ltd. | Ningbo Hi-Tech Biochemicals Co., Ltd. | Suzhou Sibian Chemical Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | API Vanguard | ChengDu KaiXin Technology Development Co., Ltd. | Hefei Photochem Trading Co., Ltd | King Tang Chemical Group Industry Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Watson International Ltd | BOC Sciences | Wolves R&D Chemicals | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Green Fine Chemical (Shanghai) Co., Ltd. | scienTEST | Clearsynth Canada INC. | Haihang Industry Co., Ltd.

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