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Intermediate of Sitagliptin phosphate

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Formula: C6H7F3N4
CAS: 486460-21-3

Identification

Structural Formula
Intermediate of Sitagliptin phosphate
CAS:
486460-21-3
EINECS:
Molecular Formula:
C6H7F3N4
MDL:
MFCD08460920
Synonym:
tap-4 (sitagliptin intermediate) ; 3-(三氟甲基)-5,6,7,8-四氢-[1,2,4]三唑并[4,3-a]吡嗪盐酸盐 ; 3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]piperazine hydrochloride ; (trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazlol[4,3-a]pyrazine ; 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyra ; 3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4] ; 3-trifluoro methyl-[1,2,4]triazole[4,3-a]piperazine ; 3-trifluoromethyl-5,6,7,8... ; 3-(trifluoromethyl)-5h,6h,7h,8h-[1,2,4]triazolo[4,3-a]pyrazine ; 3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]piperazine




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3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZINE
CM Fine Chemicals
CFC809232368
3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZINE
Leap Chem Co., Ltd
LC856825704
3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZINE
Shanghai Hanhong Scientific Co., Ltd.
SHS1761270448
3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZINE
Pharmacore Co., Limited
PL1094832844
5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine
Key Organics Limited
PS-6410
3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-1,2,4-TRIAZOLO-[4,3-A]PYRAZINE
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC42031
3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Indofine Chemical Co, Inc.
08-5642
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Helpsyn Chemical Co., Ltd
HC1207536225
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
ShangHai Biochempartner Co., Ltd.
BCP13460
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Manchester Organics Limited
S51881
3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Jiwan Pharmaceutical Technology Co., Ltd.
JPT1980379212
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Xiamen Equation Chemical Co.,Ltd
XECC1545677280
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Hangzhou Verychem Science & Technology Co., Ltd.
HVST23184115920
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Gihi Chemicals Co., Limited
GCL1304152164
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Allfluoro Pharmaceutical Co. Ltd.
APC1593963756
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Xiamen Hisunny Chemical Co., Ltd.
XHC1593963756
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Dayang Chem (Hangzhou) Co.,Ltd.
DC1497359892
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI33327133308
3-Trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine hydrochloride
Chemieliva Pharmaceutical Co., Ltd.
CP1701051030
3-Trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine hydrochloride
Hangzhou J&H Chemical Co., Ltd.
HJC1506660264
3-Trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine hydrochloride
Haihang Industry Co., Ltd.
HI1263637908
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
Capot Chemical Co., Ltd.
18203
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
Finetech Industry Limited
FIL1660066400
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
Chemlyte Solutions
CS1195235856

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Properties for Intermediate of Sitagliptin phosphate

Molecular Weight:
192.14 g·mol−1
Density:
1.72
Boiling point:
266∶C
Flash point:
115∶C
Physical Description:
white crystalline powder
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Hazard Symbols:
Xi
Hazard symbol Xi
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Alternative Distributors of [Intermediate of Sitagliptin phosphate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Beijing Hope International Pharmaceutical Tec & Dep Co., Ltd.

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MSDS:
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