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Imiquimod

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Formula: C14H16N4
CAS: 99011-02-6
search Element: imiquimod

Identification

Structural Formula
Imiquimod
CAS:
99011-02-6
EINECS:
Molecular Formula:
C14H16N4
MDL:
MFCD00866946
SMILES:
CC(C)CN1C=NC2=C1C1=C(C=CC=C1)N=C2N
Synonym:
aldara ; 4-amino- 1-isobutyl-1h-imidazo[4,5-c]quinoline ; imiquimod(aldara,r 837) ; imiquimod (aldara) ; imiquimod solution,100ppm ; 1-isobutyl-1h-imidazo[4,5-c]quinolin-4-amine ; imiquimod ; s-26308 ; r-837 ; imiquimod (200 mg)


Description

Imiquimod is a derivative of imidazoquinolinamine that inhibits angiogenesis and is an immune response modifier. Studies have reported that Imiquimod has the ability to downregulate metastasis and induce alpha-interferon (IFN-α). Additionally, Imiquimod is a TLR7 (toll-like receptor 7) agonist which induces plasmacytoid dendritic cell (pDC) maturation. Imiquimod acts on dendritic cells expressing TLR7, and induces an immune response. Nuclear factor-B helps mediate the activity of Imiquimod, and is involved in increasing chemokine and cytokine levels. The antiangiogenic property of Imiquimod has been shown to be mediated by IL-18. Research shows that Imiquimod can induce apoptosis in cancer cells. Also suggested to be an activator of caspase-3 and NFκB.


Suppliers

H&Z Industry Co.,Ltd
HIC180720
Shandong SanYoung Industry Co., Ltd
SSI3151260
Chemlyte Solutions
CS162486
Autech Industry Co.,Limited
AIC243972
Ambeed, Inc.
A161049
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6212484
Shandong Minglang Chemical Co., Ltd
SMC3151260
Gyma Laboratories Of America, Inc.
GLOA3061530
Suan Farma, Inc
SFI135540
Hangzhou Ocean Chemical Co., Ltd.
HOC2971188
Kingreat Chemistry Company Limited
KCCL3061530
Xiamen Equation Chemical Co.,Ltd
XECC2881440
CSNpharm, Inc.
CSN13134
Hangzhou Lingrui Chemical Co., Ltd.
HLC3151260
Wanko Chemical Co., Ltd.
WC216648
scienTEST - bioKEMIX GmbH
S-B225900
Hangzhou Ocean Chemical Co., Ltd.
HOC2971188
Finetech Industry Limited
FIL225900
Carbone Scientific Co., Ltd.
CS252756
CM Fine Chemicals
CFC153612
AK Scientific, Inc.
AS171513
Xingrui Industry Co., Limited
XIL2611044
BOC Sciences
BS108324
Amadis Chemical Company Limited
ACCL2791395
Leap Chem Co., Ltd
LC162486
Santa Cruz Biotechnology, Inc.
200385
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CAS equal suppliers

Aldara
Fox Chemicals GmbH
FC108324
Imiquimod, 99%
Alfa (A Johnson Matthey Company)
A4481344
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
BLD Pharmatech Ltd
BP396011880
4-amino- 1-isobutyl-1h-imidazo(4,5-c)quinoline
Hangzhou J&H Chemical Co., Ltd.
HJC713028520
1H-imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-
Angene International Limited
AGN-PC-0JL20R

Prices & Availability




Data is processed


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Properties for Imiquimod

Molecular Weight:
240.3 g·mol−1
Density:
1.28 g/cm3 (Predicted)
Melting point:
292-294 °C
Boiling point:
456.71 °C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (4 mg/ml ,warming to 60 °C for 15 minutes) DMF (1.5 mg/ml) at 37 °C, and water (slightly soluble) at 37 °C. Insoluble in ethanol.
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S27 - Take off immediately all contaminated clothing
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T, Xi
Hazard symbol T Hazard symbol Xi
Storage temperature :
Store at +4 °C
RID/ADR certification :
UN 2811 6.1 / PG 3
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Alternative Distributors of [Imiquimod]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Finetech Industry Limited | BOC Sciences | Inter-Chemical Ltd. | Jinan Great Chemical Co., Ltd. | TCS INDUSTRY LTD. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | New Dragon Industrial Co., Ltd | Watson International Ltd | Ningbo Zhengrun Chemicals Co., Ltd. Exp. Dept. | Molekula GmbH | Hangzhou Think Chemical Co., Ltd. | scienTEST | Taizhou Creating Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Clearsynth Canada INC. | Suzhou Rovathin Pharmatech Co., Ltd | Discovery Fine Chemicals Limited | Suzhou Vosun Chemical Co.,Ltd. | Haihang Industry Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Shanghai Arbor Chemical Co., Ltd. | Tocopharm Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Hubei Yuancheng Saichuang Tech.Co.,Ltd

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