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Ibuprofen

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Formula: C13H18O2
CAS: 15687-27-1
search Element: ibuprofen

Identification

Structural Formula
Ibuprofen
CAS:
15687-27-1
EINECS:
239-784-6
Molecular Formula:
C13H18O2
MDL:
MFCD00010393
SMILES:
CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
Synonym:
rufen ; dolgin ; andran ; bluton ; brufen ; advil ; ip-82 ; rufin ; dolgit ; adran


Description

Ibuprofen inhibits Cox (cyclooxygenase) selectively, targeting Cox-1 (PGH synthase-1) with an IC50 of 13 μM, and Cox-2 (PGH synthase-2) with an IC50 of 370 μM. Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6212484
Aozeal Certified Standards (AOCS), Inc.
I0001.00
Krada CPS Industry S.L
KCIS198990
Ambeed, Inc.
A238702
Chemlyte Solutions
CS162486
FUDI Chemical Co. Ltd.
FCC198792
Shandong Ench Chemical Co.,Ltd
SECC2701350
Shandong Minglang Chemical Co., Ltd
SMC3151260
H&Z Industry Co.,Ltd
HIC180720
Autech Industry Co.,Limited
AIC243972
Kum Yang Co., Ltd.
KY162486
Pharma Greven GmbH
PG162486
CellMark AB
CA99297
AXO Industry SA
AIS135540
Shanghai Worldyang Chemical Co., Ltd.
SWC3331332
Anderson & Steinssen Inc
ASI216864
Xiamen Equation Chemical Co.,Ltd
XECC2881440
Sancai Industry Co.,Ltd.
SIC216864
Hainan Zhongxin Chemical Co., Ltd.
HZC3061224
Aecochem Corp.
AC126378
CSNpharm, Inc.
CSN11183
Hangzhou Keying Chem Co., Ltd.
HKC2701080
Wanko Chemical Co., Ltd.
WC216648
Sigma-Aldrich International GmbH
SI288864
Finetech Industry Limited
FIL225900
Carbone Scientific Co., Ltd.
CS252756
Hefei Hirisun Pharmatech Co., Ltd
HR010090
Xingrui Industry Co., Limited
XIL2611044
Capot Chemical Co., Ltd.
16054
BOC Sciences
BS108324
Leap Chem Co., Ltd
LC162486
Santa Cruz Biotechnology, Inc.
200534
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Prices & Availability




Data is processed


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Properties for Ibuprofen

Molecular Weight:
206.28 g·mol−1
Density:
~1.0 g/cm3 (Predicted)
Melting point:
77-78 °C(lit.)
Boiling point:
157 °C (4 mmHg)
Solubility:
Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate. Insoluble in water.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R63 - Possible risk of harm to the unborn child
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
S7 - Keep container tightly closed
Hazard Classes:
6.1(b)
Hazard Symbols:
Xn, N, T, F
Hazard symbol T Hazard symbol N Hazard symbol F Hazard symbol Xn
Storage temperature :
-20°C Freezer
RID/ADR certification :
2811
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Alternative Distributors of [Ibuprofen]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Inter-Chemical Ltd. | Santec Chemicals Corp. | IOL Chemicals and Pharmaceuticals Ltd | Hallochem Pharma Co., Ltd. | 3B Scientific Corporation | Xiang Ding Chemical International Co., Ltd | Ningbo Pangs Chem Int'l Co., Ltd. | Changzhou An-Yuan Imp. & Exp. Corporation | New Dragon Industrial Co., Ltd | G. Amphray Laboratories | Jinan Victory Imp. & Exp. Co., Ltd. | B.M. Import & Export Ltd. | Discovery Fine Chemicals Limited | Formax Chemicals Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Shanxi Zishan Natural Technology Co., Ltd. | Jinan Great Chemical Co., Ltd. | Jinjiangchem Corporation | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Hubei MaxSource Chem Co., Ltd. | Hefei Photochem Trading Co., Ltd | Watson International Ltd | BOC Sciences | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Apollo Healthcare Resources | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Trademax Phamaceuticals & Chemicals Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | Gihi Chemicals Co., Limited | Yangzhou Princechem Co., Ltd. | Wanko Chemical Co., Ltd. | Haihang Industry Co., Ltd.

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