Ibuprofen | CAS 15687-27-1 | Chemical-Suppliers

Element: ibuprofen

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C-S » Chemicals » ibuprofen-PX485668

Identification

Ibuprofen

CAS:

15687-27-1

EINECS:

239-784-6

Molecular Formula:

C₁₃H₁₈O₂

MDL:

MFCD00010393

SMILES:

CC(C)CC1=CC=C(C=C1)C(C)C(O)=O

Synonym:

rufen ; dolgin ; andran ; bluton ; brufen ; advil ; ip-82 ; rufin ; dolgit ; adran

Description

Ibuprofen inhibits Cox (cyclooxygenase) selectively, targeting Cox-1 (PGH synthase-1) with an IC₅₀ of 13 μM, and Cox-2 (PGH synthase-2) with an IC₅₀ of 370 μM. Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23.

Suppliers

Shandong Minglang Chemical Co., Ltd

SMC3151260

H&Z Industry Co.,Ltd

HIC180720

Autech Industry Co.,Limited

AIC243972

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6212484

Aozeal Certified Standards (AOCS), Inc.

I0001.00

Ambeed, Inc.

A238702

Krada CPS Industry S.L

KCIS198990

Chemlyte Solutions

CS162486

FUDI Chemical Co. Ltd.

FCC198792

Shandong Ench Chemical Co.,Ltd

SECC2701350

Kum Yang Co., Ltd.

KY162486

Pharma Greven GmbH

PG162486

CellMark AB

CA99297

AXO Industry SA

AIS135540

Shanghai Worldyang Chemical Co., Ltd.

SWC3331332

Anderson & Steinssen Inc

ASI216864

Xiamen Equation Chemical Co.,Ltd

XECC2881440

Sancai Industry Co.,Ltd.

SIC216864

Hainan Zhongxin Chemical Co., Ltd.

HZC3061224

Aecochem Corp.

AC126378

CSNpharm, Inc.

CSN11183

Hangzhou Keying Chem Co., Ltd.

HKC2701080

Wanko Chemical Co., Ltd.

WC216648

Sigma-Aldrich International GmbH

SI288864

Finetech Industry Limited

FIL225900

Carbone Scientific Co., Ltd.

CS252756

Hefei Hirisun Pharmatech Co., Ltd

HR010090

Xingrui Industry Co., Limited

XIL2611044

Capot Chemical Co., Ltd.

16054

BOC Sciences

BS108324

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

200534

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Prices & Availability

Data is processed

Properties for Ibuprofen

Molecular Weight:

206.28 g·mol−1

Density:

~1.0 g/cm³ (Predicted)

Melting point:

77-78 °C(lit.)

Boiling point:

157 °C (4 mmHg)

Solubility:

Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate. Insoluble in water.

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R22 - Harmful if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R63 - Possible risk of harm to the unborn child

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
S7 - Keep container tightly closed

Hazard Classes:

6.1(b)

Hazard Symbols:

Xn, N, T, F
Hazard symbol T

Storage temperature :

-20°C Freezer

RID/ADR certification :

2811

Alternative Distributors of [Ibuprofen]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified