Hypothemycin | CAS 76958-67-3 | Chemical-Suppliers

Element: hypothemycin

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C-S » Chemicals » hypothemycin-PX67533

Identification

Hypothemycin

CAS:

76958-67-3

EINECS:

Molecular Formula:

C₁₉H₂₂O₈

MDL:

MFCD08457932

SMILES:

CC1C/C=C/C(=O)C2C(O2)CC(C(C3=CC(=CC(=C3C(=O)O1)O)OC)O)O

Synonym:

hypothemycin ; (1ar,3s,4s,6z,9s,15br)-1a,8,9,15b-tetrahydro-3,4,12-trihydroxy-14-methoxy-9-methyl-3h-oxireno[k][2]benzoxacyclotetradecin-5,11(2h,4h)-dione ; (1ar,3s,4s,6z,9s,15br)-1a,2,4,5,11,8,9,15b-octahydro-3,4,12-trihydroxy-9-methyl-14-methoxy-3h-oxireno[k][2]benzoxacyclotetradecin-5,11-dione ; nsc354462 ; 3h-oxireno[k][2]benzoxacyclotetradecin-5,11(2h,4h)-dione,1a,8,9,15b-tetrahydro-3,4,12-trihydroxy-14-methoxy-9-methyl-,(1ar,3s,4s,6z,9s,15br)- ; hypothemicin ; f 152 d2 ; (1ar,3s,4s,6z,9s,15br)-1a,8,9,15b-tetrahydro-3,4,12-trihydroxy-9-methyl-14-methoxy-3h-oxireno[k][2]benzoxacyclotetradecin-5,11(2h,4h)-dione

Description

Hypothemycin exhibits antifungal and cytotoxic activity against some tumor cell lines partly attributed to inhibition of Ras-inducible genes. Hypothemycin facilitates the ubiquitinylation process of cyclin D1. Hypothemycin has been identified as a potent and selective inhibitor of threonine/tyrosine-specific kinase, MEK, and other protein kinases that contain a conserved cysteine residue in the ATP-binding site in in vitro studies.

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Leap Chem Co., Ltd

LC216648

Santa Cruz Biotechnology, Inc.

203078

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Data is processed

Properties for Hypothemycin

Molecular Weight:

378.37 g·mol−1

Density:

~1.3 g/cm³ (Predicted)

Melting point:

170-172°C

Boiling point:

~667.8° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (10 mg/ml), and acetone. Insoluble in water, methanol, and deionized water.

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed

Hazard Symbols:

Storage temperature :

?20 °C

Alternative Distributors of [Hypothemycin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | BOC Sciences

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