Hydroxythiohomo Sildenafil | CAS 479073-82-0

Element: hydroxythiohomo sildenafil

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C-S » Chemicals » hydroxythiohomo-sildenafil-PX76735

Identification

Hydroxythiohomo Sildenafil

CAS:

479073-82-0

EINECS:

Molecular Formula:

C₂₃H₃₂N₆O₄S₂

MDL:

SMILES:

OCCN1CCN(CC1)S(=O)(=O)c1ccc(OCC)c(c1)c1[nH]c(=S)c2n(C)nc(CCC)c2n1

Synonym:

hydroxythiohomosildenafil ; 4-[[3-(4,7-dihydro-1-methyl-3-propyl-7-thioxo-1h-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxypheny ; 5-[2-ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7h-pyrazolo[4,3-d]pyrimidine-7-thione

Description

Hydroxythiohomo Sildenafil is a thio analog of Sildenafil (SC-338584) which has been reported to be a PDE5 inhibitor. Sildenafil is a selective inhibitor of type 5 cGMP phosphodiesterase (PDE5), which catalyzes teh hydrolysis of cGMP, an important secondary messenger molecule in a variety of cellular processes. Sildenafil has been reported to enhance angiogenesis in rat models of stroke and also has been reported to be a mild vasodilator. Sildenafil has been shown to prevent indomethacin-induced small intestinal ulceration formation throuh an NO/cGMP-dependent mechanism.

Suppliers

Aozeal Certified Standards (AOCS), Inc.

S0005.37

Santa Cruz Biotechnology, Inc.

207746

Dayang Chem (Hangzhou) Co.,Ltd.

DC16126448

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Prices & Availability

Data is processed

Properties for Hydroxythiohomo Sildenafil

Molecular Weight:

520.66798 g·mol−1

Melting point:

174-177°C

Safety & Transport Information

Storage temperature :

Refrigerator

Alternative Distributors of [Hydroxythiohomo Sildenafil]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC.

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MSDS:

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