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(S)-10-Hydroxycamptothecin

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Formula: C20H16N2O5
CAS: 19685-09-7
search Element: hydroxycamptothecin
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Identification

Structural Formula
(S)-10-Hydroxycamptothecin
CAS:
19685-09-7
EINECS:
Molecular Formula:
C20H16N2O5
MDL:
MFCD00189425
SMILES:
CC[C@@]1(O)C(=O)OCC2=C1C=C1N(CC3=CC4=C(C=CC(O)=C4)N=C13)C2=O
Synonym:
nsc 107124 ; hcpt ; sn38 ; 10-hydrocamptothecin ; irinotecan usp rc a ; 10-hcpt ; hydroxycamptothecin ; hydrocamptothecine ; ampule ; hydroxy-camptotheci


Description

(S)-10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis. (S)-10-Hydroxycamptothecin is an inhibitor of Topo I.


Suppliers

Ambeed, Inc.
A155153
+
CSNpharm, Inc.
CSN10390
Hangzhou Lingrui Chemical Co., Ltd.
HLC273010920
+
Leap Chem Co., Ltd
LC14044212
+
Santa Cruz Biotechnology, Inc.
205614
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CAS equal suppliers

Camptothecin Impurity
Aozeal Certified Standards (AOCS), Inc.
C0023.01
10-hydroxycamptothecin
Indofine Chemical Co, Inc.
06-089
10-hydroxycamptothecin
ShangHai Biochempartner Co., Ltd.
BCP01385
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Acinopeptide Co., Ltd.
A484968
10-Hydroxycamptothecin
Evonik ( formerly Wilshire Technologies, Inc. )
E10564224
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Nebula Chemicals Co, Ltd.
NCC5502200
10-Hydroxycamptothecin
Hefei Hirisun Pharmatech Co., Ltd
HR011041
10-Hydroxycamptothecin
3B (Wuhan) Scientific Corporation
37262178
10-Hydroxycamptothecin
Haihang Industry Co., Ltd.
HI5721716
10-Hydroxycamptothecin
Ascender Chemical Co.,Ltd
ACC5502200
10 hydroxy Camptothecin
AK Scientific, Inc.
AS8742622
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Chengdu Pufeide Biotech. Co., Ltd
CPB15186072
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Gihi Chemicals Co., Limited
GCL12424968
10 hydroxy Camptothecin
BOC Sciences
BS5521656
10-Hydroxy Camptothecin
Pharmaffiliates Analytics & Synthetics Pvt. Limited
PA 03 06530
10-Hydroxycamptothecine
Xiamen Hisunny Chemical Co., Ltd.
XHC7593036
10-Hydroxycamptothecine
Chemieliva Pharmaceutical Co., Ltd.
CP8052415
10-Hydroxycamptothecine
Leap Chem Co., Ltd
LC4141242
10-Hydroxycamptothecine
Autech Industry Co.,Limited
AIC6212484
10-Hydroxycamptothecine
Haihang Industry Co., Ltd.
HI5981794
10-Hydroxycamptothecine
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI15876348
10-Hydroxycamptothecine
Carbone Scientific Co., Ltd.
CS6441932
10-Hydroxycamptothecine
H&Z Industry Co.,Ltd
HIC4601840
10-Hydroxycamptothecine
Gihi Chemicals Co., Limited
GCL6212484
10-Hydroxycamptothecine
BOC Sciences
BS276828
10-Hydroxycamptothecine
Dayang Chem (Hangzhou) Co.,Ltd.
DC7132852
10-Hydroxycamptothecine
Zehao Industry Co., Ltd.
ZI5521656
(20S)-10-Hydroxycamptothecine
Kingreat Chemistry Company Limited
KCCL295814790
(20S)-10-Hydroxycamptothecine
Santa Cruz Biotechnology, Inc.
SCB261010440
(20S)-10-Hydroxycamptothecine
Xiamen Equation Chemical Co.,Ltd
XECC278413920
(20S)-10-Hydroxycamptothecine
Xingrui Industry Co., Limited
XIL252310092
(20S)-10-Hydroxycamptothecine
Gihi Chemicals Co., Limited
GCL23499396
(20S)-10-Hydroxycamptothecine
Simagchem Corporation
SC18275481
(S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Hangzhou MolCore BioPharmatech Co.,Ltd.
CS10952
(S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
BLD Pharmatech Ltd
BP2318469552

Prices & Availability




Data is processed


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Properties for (S)-10-Hydroxycamptothecin

Molecular Weight:
364.35 g·mol−1
Density:
1.60
Melting point:
265-270 °C
Boiling point:
820.71° C at 760 mmHg (Predicted)
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

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Alternative Distributors of [(S)-10-Hydroxycamptothecin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC.

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Downloads

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MSDS:
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