15(R),19(R)-hydroxy Prostaglandin E2 | CAS 54142-29-9

Element: prostaglandin hydroxy

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C-S » Chemicals » hydroxy-prostaglandin-PX65877

Identification

15(R),19(R)-hydroxy Prostaglandin E2

CAS:

54142-29-9

EINECS:

Molecular Formula:

C₂₀H₃₂O₆

MDL:

SMILES:

O[C@H] (CCC[C@@H] (C) O) CC[C@H] 1C(O) CC(=O) C1C/C=CCCCC(=O) O

Synonym:

9-OXO-11ALPHA,15R,19R-TRIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID ; 15(R)-19(R)-HYDROXY PROSTAGLANDIN E2 ; 15(R)-19(R)-HYDROXY PROSTAGLANDIN E2

Description

15(R),19(R)-hydroxy Prostaglandin E2 is the inverse or “unnatural” isomer at C-15 of 19(R)-Hydroxy-prostaglandin E2. These 19-hydroxylated prostaglandins have been associated with selectively agonizing EP2 receptors, contrary to PGE2, which can activate a variety of prostanoid receptor types. The ability of these 19-hydroxylated prostaglandins to selectively agonize EP2 receptors is useful in the deconvolution of EP-receptor function.