2-hydroxy Estradiol | CAS 362-05-0

Element: estradiol hydroxy

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C-S » Chemicals » hydroxy-estradiol-PX67927

Identification

2-hydroxy Estradiol

CAS:

362-05-0

EINECS:

Molecular Formula:

C₁₈H₂₄O₃

MDL:

SMILES:

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=C(C=C34)O)O

Synonym:

c05301 ; 2-oh-e2? ; nsc 61711 ; 2-oh-estradiol ; 2-hydroxyestradiol ; 2-hydroxy-17-estradiol ; 2-hydroxyestradiol-17? ; 2-hydroxy-17b-estradiol ; (17?)-2-hydroxyestradiol ; 2-hydroxyestradiol-17beta

Description

2-hydroxy Estradiol (2-HE) is rapidly metabolized by catechol-O-methyltransferase (COMT) to 2-methoxy estradiol (2-ME2) with a half-life of approximately ten minutes in rats. 2-ME2 has garnered considerable attention as an anticancer agent due to its apparent inhibition of angiogenesis. Due to the rapid metabolism of 2-HE2, the effects attributed to 2-HE2, may actually be those of 2-ME2.

Suppliers

Santa Cruz Biotechnology, Inc.

205085

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CAS equal suppliers

2-Hydroxyestradiol

Sigma-Aldrich International GmbH

SI5761728

2-Hydroxyestradiol

Dayang Chem (Hangzhou) Co.,Ltd.

DC5582232

2-Hydroxyestradiol

Santa Cruz Biotechnology, Inc.

SCB5402160

2-Hydroxy-17b-estradiol

Salsbury Chemicals, Inc.

SC11043312

2-Hydroxy-17b-estradiol

Autech Industry Co.,Limited

AIC12424968

Prices & Availability

Data is processed

Properties for 2-hydroxy Estradiol

Molecular Weight:

288.38 g·mol−1

Melting point:

96-104°C

Boiling point:

430.31° C (Predicted)

Safety & Transport Information

Risk Codes:

R40 - Limited evidence of a carcinogenic effect

Safety Codes:

S22 - Do not breathe dust
S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

-20°C

Alternative Distributors of [2-hydroxy Estradiol]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Salsbury Chemicals, Inc., | Clearsynth Canada INC.