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R 568 hydrochloride

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Formula: C18H23Cl2NO
CAS: 177172-49-5
search Element: hydrochloride

Identification

Structural Formula
R 568 hydrochloride
CAS:
177172-49-5
EINECS:
Molecular Formula:
C18H23Cl2NO
MDL:
MFCD16038895
SMILES:
C[C@H](C1=CC(=CC=C1)OC)NCCCC2=CC=CC=C2Cl.Cl
Synonym:
Tecalcet hydrochloride [USAN]


Description

R 568 hydrochloride is an activator and allosteric agonist of the CaSR (calcium-sensing receptor) via positive allosteric modulation. R 568 hydrochloride exhibits calcimimetic activity. R 568 hydrochloride has the ability to restore function to hCaSR mutants that cause familial hypocalciuric hypercalcemia (FHH) and neonatal severe hyperparathyroidism (NSHPT). R 568 hydrochloride exerts a suppressive effect on parathyroid (PT) hormone secretion.


Suppliers

Amadis Chemical Company Limited
ACCL11785890
Santa Cruz Biotechnology, Inc.
361302
Dayang Chem (Hangzhou) Co.,Ltd.
DC11784712
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Properties for R 568 hydrochloride

Molecular Weight:
340.29 g·mol−1
Boiling point:
416.3 °C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (100 mM), and ethanol (100 mM).
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Safety & Transport Information

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Alternative Distributors of [R 568 hydrochloride]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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