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A 438079 hydrochloride

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Formula: C13H9Cl2N5.HCl
CAS: 899507-36-9

Identification

Structural Formula
A 438079 hydrochloride
CAS:
899507-36-9
EINECS:
Molecular Formula:
C13H9Cl2N5.HCl
MDL:
SMILES:
C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl
Synonym:
a 438079 hydrochloride ; 3-[[5-(2,3-dichlorophenyl)-1h-tetrazol-1-yl]methyl]pyridine ; a 438079 ; 3-[[5-(2,3-dichlorophenyl)-1h-tetrazol-1-yl]methyl]pyridine hydrochloride


Description

Competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). Devoid of activity at other P2 receptors (IC50 >> 10 µM). Possesses antinociceptive activity in models of neuropathic pain in vivo.


Suppliers

Aea.ltd
A308616
Ambeed, Inc.
A152651
Amadis Chemical Company Limited
ACCL13646820
Santa Cruz Biotechnology, Inc.
203788
Dayang Chem (Hangzhou) Co.,Ltd.
DC13645456
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CAS equal suppliers

3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine
Leap Chem Co., Ltd
LC849625488
3-[[5-(2,3-Dichlorophenyl)tetrazol-1-yl]methyl]pyridine;hydrochloride
Angene International Limited
AGN-PC-00E647
A 438079 hydrochloride,3-[[5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridinehydrochloride
Chemlyte Solutions
CS1710051300

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Properties for A 438079 hydrochloride

Molecular Weight:
342.61 g·mol−1
Boiling point:
525.1° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (100 mM), and DMSO (100 mM).
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Safety & Transport Information

Storage temperature :
Desiccate at RT
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Alternative Distributors of [A 438079 hydrochloride]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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