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Y-25130 Hydrochloride

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Formula: C17H20ClN3O3.HCl
CAS: 123040-16-4
search Element: hydrochloride 25130
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Identification

Structural Formula
Y-25130 Hydrochloride
CAS:
123040-16-4
EINECS:
Molecular Formula:
C17H20ClN3O3.HCl
MDL:
MFCD00209913
SMILES:
CN1C(=O)COC2=C1C=C(C=C2C(=O)NC3CN4CCC3CC4)Cl.Cl
Synonym:
serotone ; 2h-1,4-benzoxazine-8-carboxamide,3,4-dihydro-n-1-azabicyclo(2.2.2)oct-3-yl-6-c ; azasetron hcl ; y-25130 hydrochloride ; azasetron hydrochloride ; y-25130hcl ; azastron hydrochloride injection ; azasetron ; y-25130 ; intermediate of azasetron hcl


Description

Y-25130 Hydrochloride is a potent and selective SR-3 antagonist. This product was demonstrated to be an antiemetic agent valuable for countering adverse effects seen in anticancer therapy including cisplatin. In studies involving rat hippocampal slices, Y-25130 exhibited dose-dependent neuroprotective effects against an ischemia-induced decrease in CA1 field potential. It has also been reported to attenuate the cocaine-induced decrease of intracranial self-stimulation (ICSS) reward thresholds in rats. Other results of the SR-3 antagonistic activity of Y-25130 led to the acceleration of gastric emptying in mice.


Suppliers

Santa Cruz Biotechnology, Inc.
201150
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Prices & Availability




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Properties for Y-25130 Hydrochloride

Molecular Weight:
386.27 g·mol−1
Melting point:
301-303° C
Boiling point:
558° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (25 mg/ml), and DMSO (10 mM).
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Safety & Transport Information

Storage temperature :
Desiccate at -20 °C
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Alternative Distributors of [Y-25130 Hydrochloride]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

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MSDS:
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