Homoharringtonine | CAS 26833-87-4

Element: homoharringtonine

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C-S » Chemicals » homoharringtonine-PX75749

Identification

Homoharringtonine

CAS:

26833-87-4

EINECS:

Molecular Formula:

C₂₉H₃₉NO₉

MDL:

MFCD03410264

SMILES:

CC(C)(CCC[C@](CC(=O)OC)(C(=O)O[C@H]1[C@H]2C3=CC4=C(C=C3CCN5[C@@]2(CCC5)C=C1OC)OCO4)O)O

Synonym:

myelostat ; hht ; cgx 635 ; acvrlk1 ; skr3 ; nsc 141633 ; orw2 ; acvrl1 ; hht2 ; ceflatonin

Description

Homoharringtonine is a cephalotaxine alkaloid which inhibits the formation of diphenylalanine and acetylphenylalanyl-puromycin in liver ribosomes. Homoharringtonine has promising activity in hematologic malignancies and functions as an antileukemic. Homoharringtonine blocks the elongation phase of translation by binding to the 60-S ribosome subunit. Additionally, homoharringtonine has been shown to lower telomerase levels, inhibit protein synthesis, and induce apoptosis.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI11734692

Chengdu Pufeide Biotech. Co., Ltd

CPB5612244

H&Z Industry Co.,Ltd

HIC3401360

Indofine Chemical Co, Inc.

06-686

Sinogreat Enterprise Ltd.

SE4251275

Xiamen Equation Chemical Co.,Ltd

XECC5442720

scienTEST - bioKEMIX GmbH

S-B4251700

Pharmacore Co., Limited

PL3911173

Acinopeptide Co., Ltd.

A374748

Xingrui Industry Co., Limited

XIL4931972

Leap Chem Co., Ltd

LC306918

Santa Cruz Biotechnology, Inc.

202652

Dayang Chem (Hangzhou) Co.,Ltd.

DC5272108

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CAS equal suppliers

Omacetaxine Mepesuccinate

Pharmaffiliates Analytics & Synthetics Pvt. Limited

PA 15 39000

(2R)-2-Hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate]

Autech Industry Co.,Limited

AIC1058442336

Prices & Availability

Data is processed

Properties for Homoharringtonine

Molecular Weight:

545.62 g·mol−1

Density:

~1.3 g/cm³ (Predicted)

Melting point:

144-146 C

Boiling point:

~713.1° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (100 mM), ethanol (50 mM), water (partly), chloroform, and methanol.

Safety & Transport Information

Risk Codes:

R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
R28 - Very toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S27 - Take off immediately all contaminated clothing
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

6.1(a)

Hazard Symbols:

T+, Xi

Storage temperature :

2-8°C

RID/ADR certification :

UN 1544 6.1 / PG 2

Alternative Distributors of [Homoharringtonine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

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MSDS:

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