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Histamine, free base

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Formula: C5H9N3
CAS: 51-45-6
search Element: histamine base free
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Identification

Structural Formula
Histamine, free base
CAS:
51-45-6
EINECS:
200-100-6
Molecular Formula:
C5H9N3
MDL:
MFCD00005210
SMILES:
C1=C(NC=N1)CCN
Synonym:
histamin ; l-histamine ; his elisa ; eramin ; theramine ; histamine ; ergotidine ; istamina ; eramine ; ergamine


Description

Histamine, free base is a potent vasodilator found in normal tissues and blood. This compound is formed by the decarboxylation of L-histidine and activates NOS (nitric oxide synthase), resulting in the release of nitric oxide. Activation of histamine H1 receptors leads to Ca2+ mobilization; whereas, histamine H2 receptor activation stimulates adenylate cyclase activity in neurons. Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation.


Suppliers

Santa Cruz Biotechnology, Inc.
204000
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Prices & Availability




Data is processed


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Properties for Histamine, free base

Molecular Weight:
111.15 g·mol−1
Density:
~1.1 g/cm3 (Predicted)
Melting point:
83-84 °C(lit.)
Boiling point:
167 °C0.8 mm Hg(lit.)
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R42/43 - May cause sensitization by inhalation and skin contact
Safety Codes:
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
Hazard Classes:
6.1(b)
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
-20°C
RID/ADR certification :
UN 2811 6.1 / PG 3
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Alternative Distributors of [Histamine, free base]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Salsbury Chemicals, Inc., | Shanghai AOKChem Group Limited | Sino Rarechem Labs Co. Ltd. | Wanko Chemical Co., Ltd.

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