Hispidulin | CAS 1447-88-7 | Chemical-Suppliers

Element: hispidulin

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C-S » Chemicals » hispidulin-PX77766

Identification

Hispidulin

CAS:

1447-88-7

EINECS:

Molecular Formula:

C₁₆H₁₂O₆

MDL:

MFCD00143504

SMILES:

COC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC=C(C=C3)O)O

Synonym:

hispedulin ; 5,7,4'-trihydroxy-6-methoxyflavone ; scutellarein 6-methyl ether ; hispidulin ; 4',5,7-trihydroxy-6-methoxyflavone ; 6-methoxyapigenin ; 4h-1-benzopyran-4-one,5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy- ; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4h-1-benzopyran-4-one ; 6-o-methylapigenin ; salvitin ; dinatin ; flavone,4',5,7-trihydroxy-6-methoxy- (7ci,8ci) ; 6-o-methylscutellarein ; nsc122415 ; 6-methoxy-5,7,4'-trihydroxyflavone ; 6-methylscutellarein ; methoxyapigenin ; hispidulin(dinatin)

Description

Hispidulin is a natural flavanoid which acts as a potent benzodiazepine (BZD) receptor ligand. In addition, hispidulin competitively binds to the benzodiazepine receptor, thus inhibiting 3H-Flumazenil from binding to the receptor. Furthermore, it has been observed that hispidulin has antioxidant, antithrombotic, antifungal, and antiproliferative properties. Alternate studies indicate that hispidulin can inhibit the PI3K/Akt/mTOR signaling pathway in endothelial cells by targeting VEGF receptor 2. Inhibition of this receptor by hispidulin suppressed cell migration, invasion, and capillary-like structure formation of HU-VE-Cs in vascular endothelial cells. Hispidulin also aactivates AMPK.

Suppliers

Chengdu Pufeide Biotech. Co., Ltd

CPB3301320

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6902760

Indofine Chemical Co, Inc.

06-684

Leap Chem Co., Ltd

LC180540

Santa Cruz Biotechnology, Inc.

203999

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CAS equal suppliers

4H-1-benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-

Angene International Limited

AGN-PC-0LPKF6

Prices & Availability

Data is processed

Properties for Hispidulin

Molecular Weight:

300.26 g·mol−1

Density:

1.512 g/cm3

Melting point:

207.00° C (Predicted)

Boiling point:

601.506 °C at 760 mmHg

Flash point:

230.135 °C

Solubility:

Soluble in DMSO (25 mM), and ethanol (10 mM).

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed

Hazard Symbols:

Storage temperature :

Desiccate at -20 °C

Alternative Distributors of [Hispidulin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

-/-

MSDS:

-/-

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