5(S)-HETE lactone | CAS 127708-42-3

Element: lactone hete

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C-S » Chemicals » hete-lactone-PX70736

Identification

5(S)-HETE lactone

CAS:

127708-42-3

EINECS:

Molecular Formula:

C₂₀H₃₀O₂

MDL:

Synonym:

5s-hydroxy-6e,8z,11z,14z-eicosatetraenoic acid, 1,5-lactone ; 5(s)-hete lactone

Description

5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. The ability of (±)5-HETE lactone to inhibit rat basophilic leukemia cell 5-lipoxygenase (IC₅₀ = 27 µM) may be entirely due to the 5(S) isomer, but the enantiomers have not been tested separately.

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Properties for 5(S)-HETE lactone

Molecular Weight:

302.45 g·mol−1

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MSDS:

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