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Harmine

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Formula: C13H12N2O
CAS: 442-51-3
search Element: harmine
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Identification

Structural Formula
Harmine
CAS:
442-51-3
EINECS:
207-131-4
Molecular Formula:
C13H12N2O
MDL:
MFCD00004958
SMILES:
CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC
Synonym:
garmin ; yagein ; yageine ; harmin ; telepathien ; yajeine ; telepathin ; harmine ; leucoharmine ; hal base


Description

Harmine is an alkaloid of the β-carboline family that regulates PPARγ expression. Harmine inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.


Suppliers

Chengdu Pufeide Biotech. Co., Ltd
CPB231924
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI4831932
+
Chemlyte Solutions
CS126378
+
Indofine Chemical Co, Inc.
H-005
CSNpharm, Inc.
CSN11609
Carbone Scientific Co., Ltd.
CS196588
+
AK Scientific, Inc.
AS133399
+
Leap Chem Co., Ltd
LC126378
+
Santa Cruz Biotechnology, Inc.
202644
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Prices & Availability




Data is processed


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Properties for Harmine

Molecular Weight:
212.25 g·mol−1
Density:
1.25 g/cm3 (Predicted)
Melting point:
262-264 °C(lit.)
Boiling point:
421.37° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (100 mM), DMF (~1.5 mg/ml), ethanol (~1.5 mg/ml), and PBS (pH 7.2, ~0.25 mg/ml). Insoluble in water.
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R25 - Toxic if swallowed
R36 - Irritating to eyes
Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
Hazard Classes:
6.1
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
Refrigerator
RID/ADR certification :
1544
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Alternative Distributors of [Harmine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | Biosynth AG | BOC Sciences | ABCR GmbH & Co. KG | Jinan Great Chemical Co., Ltd. | Gihi Chemicals Co., Limited | BioBioPha Co., Ltd. | TCI Europe NV | Molekula GmbH | Shanghai Hanhong Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | ChengDu KaiXin Technology Development Co., Ltd. | Carl Roth GmbH + Co KG | Suzhou Rovathin Pharmatech Co., Ltd | Suzhou Vosun Chemical Co.,Ltd. | Chengdu Conut Intl. Co., Ltd. | East Chemical Industry Co., Ltd. | Wanko Chemical Co., Ltd.

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Downloads

Mol File:
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MSDS:
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