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Guanidine Hydrochloride

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Formula: CH5N3.HCl
CAS: 50-01-1

Identification

Structural Formula
Guanidine Hydrochloride
CAS:
50-01-1
EINECS:
200-002-3
Molecular Formula:
CH5N3.HCl
MDL:
MFCD00013026
SMILES:
C(=N)(N)N.Cl
Synonym:
guanidium chloride ; gdmcl ; guanidinium chloride ; guanidine hci ; aminoformamidine hcl ; guhy ; usafek-749 ; guanidine hydr ; guanidinechloride ; guanidine hcl


Description

Guanidine Hydrochloride is a powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids. Guanidine Hydrochloride is useful for denaturation and refolding of proteins as well as in the recovery of periplasmic proteins and isolation of RNA. At higher concentrations, this strong denaturant has been reported to solubilize denatured insoluble proteins such as inclusion bodies. When utilized at lower concentrations, Guanidine Hydrochloride is noted to be useful in prompting the refolding of denatured proteins. Guanidine Hydrochloride is also been reported to allow return of enzymatic activity in protocols using Guanidine Hydrochloride as a first step. Guanidine Hydrochloride is an inhibitor of RNase.


Suppliers

Yixing TRY New Materials Co.,Ltd.
YTNMC15189108
Shandong Minglang Chemical Co., Ltd
SMC16106440
Shandong SanYoung Industry Co., Ltd
SSI16106440
Lori Industry Co., Ltd
LI10123036
Nantong Xindao Biotech Ltd
NXB11964784
Refine Chemical Co.,Ltd.
RCC11044416
Create Chemical Co., Ltd.
CC11503450
BLD Pharmatech Ltd
BP8282484
Chemlyte Solutions
CS8282484
Shandong Lanhai Industry Co.,Ltd.
SLIC15187590
H&Z Industry Co.,Ltd
HIC9203680
Autech Industry Co.,Limited
AIC12424968
XD BIOCHEMS Ltd
XB6902070
Krada CPS Industry S.L
KCIS10125060
Fountain Biotechnology Co.,Ltd
FBC13805520
OPQ Chemical Co., Ltd
OC9662898
Shandong Ench Chemical Co.,Ltd
SECC13806900
Wuhan PharmChem Co., LTD.
WP11503450
Biovectra Dcl
BD5981794
Doe & Ingalls, Inc.
DI8742622
Amresco Inc.
A5521104
Indofine Chemical Co, Inc.
Bio-192
VWR International, LLC ( United Biochemicals )
29110-KI
Henan Haofei Chemical Co.,Ltd
HHCC13346670
Fabrichem, Inc.
F6901380
Alzchem Trostberg GmbH
AT10123036
Evonik Industries AG
EIA9203680
X´ian Taicheng Chem Co., Ltd
XTC13345336
Hangzhou Verychem Science & Technology Co., Ltd.
HVST220811040
Shanghai Yayu Biomedical Co., Ltd
SYB15186072
Shanghai Mintchem Development Co., Ltd.
SMD17947176
Shanghai Worldyang Chemical Co., Ltd.
SWC17026808
Xiamen Equation Chemical Co.,Ltd
XECC14727360
Hangzhou Zhongqi Chem Co., Ltd
HZC13805520
Sancai Industry Co.,Ltd.
SIC11044416
Hainan Zhongxin Chemical Co., Ltd.
HZC15646256
Daming Changda Co., Ltd.
LLB00634
Aecochem Corp.
AC6441932
Hangzhou Keying Chem Co., Ltd.
HKC13805520
Hangzhou Lingrui Chemical Co., Ltd.
HLC16106440
scienTEST - bioKEMIX GmbH
S-B11504600
Finetech Industry Limited
FIL11504600
Xiamen Hisunny Chemical Co., Ltd.
XHC15186072
AK Scientific, Inc.
AS8742622
Xiamen Kinbester Co., Ltd.
XK11963588
Simagchem Corporation
SC9662898
Xingrui Industry Co., Limited
XIL13345336
Zehao Industry Co., Ltd.
ZI11043312
Leap Chem Co., Ltd
LC8282484
Santa Cruz Biotechnology, Inc.
202637
Dayang Chem (Hangzhou) Co.,Ltd.
DC14265704
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Prices & Availability




Data is processed


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Properties for Guanidine Hydrochloride

Molecular Weight:
95.53 g·mol−1
Density:
1.18 g/mL at 25 °C(lit.)
Melting point:
180-185 °C(lit.)
Solubility:
H2O: 6 M, clear, colorless
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin
Safety Codes:
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xn, Xi
Hazard symbol Xn Hazard symbol Xi
Storage temperature :
Store at RT.
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Alternative Distributors of [Guanidine Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Rongkang Industry Co.,Ltd - (NSTU Chemicals Hanggzhou Co.,) | Hebei Smart Chemicals Co., Ltd. | Hangzhou Electrochemical Group Co.,Ltd | Molekula GmbH | Chem-Impex International, Inc. | Shanghai Trico Int´l Trade Co., Ltd. | S.B. Organics Limited | Xiang Ding Chemical International Co., Ltd | ABCR GmbH & Co. KG | TCI Europe NV | Gain Charm International Ltd. | Chemwill Asia Co.,Limited | Suzhou Rovathin Pharmatech Co., Ltd | Azelis Deutschland GmbH | Ark Pharm, Inc. | Suzhou Yacoo Chemical Reagent Corporation | Shanghai Hanhong Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Tai Hua Industries Co., Limited | Carl Roth GmbH + Co KG | Bichem Lab Co., Ltd. | 3Way Pharm Inc. | East Chemical Industry Co., Ltd. | Discovery Fine Chemicals Limited | Tianjin Boai NKY International Ltd. | Watson International Ltd | Mascot I.E. Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Pfaltz & Bauer, Inc. | Sino Rarechem Labs Co. Ltd. | Angel Synthesis Co., Ltd | scienTEST | Ningbo EST Chemical Co., Ltd | Clearsynth Canada INC.

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