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Glimepiride

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Formula: C24H34N4O5S
CAS: 93479-97-1
search Element: glimepiride

Identification

Structural Formula
Glimepiride
CAS:
93479-97-1
EINECS:
Molecular Formula:
C24H34N4O5S
MDL:
MFCD00878417
SMILES:
CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC2CC[C@H](C)CC2)C1=O
Synonym:
amary ; glimperide ; glimpiride ; climepiride ; amaryl ; grimepride ; glimepirid ; glimepiride ; hoe490 ; glimipride


Description

Glimepiride is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle suggest that Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases protein expression of glucose transports 1 and 4, and is a potent KIR channel blocker.


Suppliers

Ambeed, Inc.
A552202
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI7593036
Chemlyte Solutions
CS198594
Gyma Laboratories Of America, Inc.
GLOA3741870
Cangzhou Goldlion Chemicals Co., Ltd.
CGC4071628
Suan Farma, Inc
SFI165660
Alfa (A Johnson Matthey Company)
A3521056
Xiamen Equation Chemical Co.,Ltd
XECC3521760
Sancai Industry Co.,Ltd.
SIC2641056
Hainan Zhongxin Chemical Co., Ltd.
HZC3741496
Aecochem Corp.
AC154462
CSNpharm, Inc.
CSN16794
Hangzhou Lingrui Chemical Co., Ltd.
HLC3851540
Sigma-Aldrich International GmbH
SI3521056
scienTEST - bioKEMIX GmbH
S-B2751100
Finetech Industry Limited
FIL2751100
Carbone Scientific Co., Ltd.
CS308924
AK Scientific, Inc.
AS209627
Xingrui Industry Co., Limited
XIL3191276
BOC Sciences
BS132396
Leap Chem Co., Ltd
LC198594
Santa Cruz Biotechnology, Inc.
203058
Dayang Chem (Hangzhou) Co.,Ltd.
DC3411364
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CAS equal suppliers

N-(3-Ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-3-(4-(N-((4-methylcyclohexyl)carbamoyl)sulfamoyl)phenyl)propanamide
Wanko Chemical Co., Ltd.
WC46464139392
3-Ethyl-4-methyl-N-(4-(N-((rel-(1R,4R)-4-methylcyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
BLD Pharmatech Ltd
BP40086120258
Glimepirid; Glimpiride; 1-[[4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-ylcarbonyl)amino]ethyl]phenyl]sulfonyl]-3-(4α-methylcyclohexan-1β-yl)urea
Shanghai UCHEM Inc.
UCHEM-6116

Prices & Availability




Data is processed


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Properties for Glimepiride

Molecular Weight:
490.62 g·mol−1
Density:
1.30 g/cm3 (Predicted)
Melting point:
212.2-214.5 °C
Boiling point:
750.37° C (Predicted)
Solubility:
DMSO: >10 mg/mL
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Safety & Transport Information

Risk Codes:
R21 - Harmful in contact with skin
R36/38 - Irritating to eyes and skin
R46 - May cause inheritable genetic damage
R62 - Possible risk of impaired fertility
R63 - Possible risk of harm to the unborn child
Safety Codes:
S25 - Avoid contact with eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
Xn, Xi
Hazard symbol Xn Hazard symbol Xi
Storage temperature :
Room temp
x

Alternative Distributors of [Glimepiride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Inter-Chemical Ltd. | Ningbo Zhengrun Chemicals Co., Ltd. Exp. Dept. | Xianju Chuangye Chemical Factory | Argosi International Co., Ltd. | 3B Scientific Corporation | Hangzhou Think Chemical Co., Ltd. | Molekula GmbH | Zhejiang Jiangbei Pharmaceutical Co., Ltd. | Afine Chemicals Limited | Xiang Ding Chemical International Co., Ltd | Qichun QiLong Chemical Co., Ltd. | Pharmasi Chemicals Co., Ltd. | Zhejiang Materials Industry Chemical Group Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Jiangsu Xinyi Huili Fine Chemical Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Synfine Research Inc. | New Dragon Industrial Co., Ltd | Dishman Europe Ltd. | Hana Pharm. Co., Ltd. | Conier Chem & Pharma Ltd | Zibo Panxin Pharmaceutical Co., Ltd. | Formax Chemicals Co., Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Qingdao Sunrisechem Co., Ltd. | Share Chemical Co., Ltd. | Abtonsmart Chemicals Co., Ltd. | Atomole Scientific Co., Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Lanospharma Laboratories Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Nantong Qihai Chemicals Co., Ltd. | Ningbo Hi-Tech Biochemicals Co., Ltd. | Bichem Lab Co., Ltd. | Shanghai Insight Chemicals Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Taizhou Creating Chemical Co., Ltd. | King Tang Chemical Group Industry Co., Ltd. | Watson International Ltd | Aopharm | BOC Sciences | Apollo Healthcare Resources | Finetech Industry Limited | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Sino Rarechem Labs Co. Ltd. | scienTEST | Clearsynth Canada INC. | Wanko Chemical Co., Ltd. | Haihang Industry Co., Ltd.

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