Glimepiride | CAS 93479-97-1 | Chemical-Suppliers

Element: glimepiride

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C-S » Chemicals » glimepiride-PX485702

Identification

Glimepiride

CAS:

93479-97-1

EINECS:

Molecular Formula:

C₂₄H₃₄N₄O₅S

MDL:

MFCD00878417

SMILES:

CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC2CC[C@H](C)CC2)C1=O

Synonym:

amary ; glimperide ; glimpiride ; climepiride ; amaryl ; grimepride ; glimepirid ; glimepiride ; hoe490 ; glimipride

Description

Glimepiride is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle suggest that Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases protein expression of glucose transports 1 and 4, and is a potent KIR channel blocker.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI7593036

Chemlyte Solutions

CS198594

Ambeed, Inc.

A552202

Gyma Laboratories Of America, Inc.

GLOA3741870

Cangzhou Goldlion Chemicals Co., Ltd.

CGC4071628

Suan Farma, Inc

SFI165660

Alfa (A Johnson Matthey Company)

A3521056

Xiamen Equation Chemical Co.,Ltd

XECC3521760

Sancai Industry Co.,Ltd.

SIC2641056

Hainan Zhongxin Chemical Co., Ltd.

HZC3741496

Aecochem Corp.

AC154462

CSNpharm, Inc.

CSN16794

Hangzhou Lingrui Chemical Co., Ltd.

HLC3851540

Sigma-Aldrich International GmbH

SI3521056

scienTEST - bioKEMIX GmbH

S-B2751100

Finetech Industry Limited

FIL2751100

Carbone Scientific Co., Ltd.

CS308924

AK Scientific, Inc.

AS209627

Xingrui Industry Co., Limited

XIL3191276

BOC Sciences

BS132396

Leap Chem Co., Ltd

LC198594

Santa Cruz Biotechnology, Inc.

203058

Dayang Chem (Hangzhou) Co.,Ltd.

DC3411364

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CAS equal suppliers

N-(3-Ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-3-(4-(N-((4-methylcyclohexyl)carbamoyl)sulfamoyl)phenyl)propanamide

Wanko Chemical Co., Ltd.

WC46464139392

3-Ethyl-4-methyl-N-(4-(N-((rel-(1R,4R)-4-methylcyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide

BLD Pharmatech Ltd

BP40086120258

Glimepirid; Glimpiride; 1-[[4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-ylcarbonyl)amino]ethyl]phenyl]sulfonyl]-3-(4α-methylcyclohexan-1β-yl)urea

Shanghai UCHEM Inc.

UCHEM-6116

Prices & Availability

Data is processed

Properties for Glimepiride

Molecular Weight:

490.62 g·mol−1

Density:

1.30 g/cm³ (Predicted)

Melting point:

212.2-214.5 °C

Boiling point:

750.37° C (Predicted)

Solubility:

DMSO: >10 mg/mL

Safety & Transport Information

Risk Codes:

R21 - Harmful in contact with skin
R36/38 - Irritating to eyes and skin
R46 - May cause inheritable genetic damage
R62 - Possible risk of impaired fertility
R63 - Possible risk of harm to the unborn child

Safety Codes:

S25 - Avoid contact with eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S53 - Avoid exposure - obtain special instructions before use

Hazard Symbols:

Xn, Xi

Storage temperature :

Room temp

Alternative Distributors of [Glimepiride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified