Genistein | CAS 446-72-0 | Chemical-Suppliers

Element: genistein

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C-S » Chemicals » genistein-PX233172

Identification

Genistein

CAS:

446-72-0

EINECS:

207-174-9

Molecular Formula:

C₁₅H₁₀O₅

MDL:

MFCD00016952

SMILES:

C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O

Synonym:

gen ; prunetol ; glyciten ; genivida ; npi 031l ; c.i.75610 ; genisteol ; genistein ; genestein ; bonistein

Description

Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK). Additionally, Genistein is a competitive inhibitor of ATP in other protein kinase reactions. Genistein inhibits tyrosine phosphorylation in isolated enzyme and receptor preparations and in whole cells including platelets, lymphocytes and a variety of cultured cells. It also inhibits EGF-stimulated phosphorylation in cultured cells as well as inhibition of Topo II (topoisomerase II). In cultured A431 epidermoid carcinoma cells, EGF-stimulated tyrosine phosphorylation was completely inhibited by genistein at 100 μg/ml. Inhibition is competitive with ATP and noncompetitive with substrate. Genistein also acts as an agonist at the GPR30 receptor and binds to PPARγ and estrogen receptors. Genistein also binds to PPARγ, acting as an agonist at this receptor and has been shown to acitvate CFTR (cystic fibrosis transmembrane conductance regulator) chlorine channels in some studies. Genistein is an inhibitor of Glucosidase.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6212484

Chengdu Pufeide Biotech. Co., Ltd

CPB2971188

Shandong Ench Chemical Co.,Ltd

SECC2701350

H&Z Industry Co.,Ltd

HIC180720

Autech Industry Co.,Limited

AIC243972

Ambeed, Inc.

A107459

Chemlyte Solutions

CS162486

Indofine Chemical Co, Inc.

G-103

A.G. Scientific

AS135405

Chematek S.p.A.

CS135405

Sinogreat Enterprise Ltd.

SE225675

X´ian Taicheng Chem Co., Ltd

XTC2611044

Xiamen Equation Chemical Co.,Ltd

XECC2881440

Aecochem Corp.

AC126378

CSNpharm, Inc.

CSN18651

Hangzhou Lingrui Chemical Co., Ltd.

HLC3151260

Sigma-Aldrich International GmbH

SI288864

scienTEST - bioKEMIX GmbH

S-B225900

Finetech Industry Limited

FIL225900

Pharmacore Co., Limited

PL207621

Iris Biotech GmbH

LS-1032.0000

AK Scientific, Inc.

AS171513

Xiamen Kinbester Co., Ltd.

XK234702

Simagchem Corporation

SC189567

Xingrui Industry Co., Limited

XIL2611044

BOC Sciences

BS108324

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

3515

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CAS equal suppliers

genistein with hplc

Indofine Chemical Co, Inc.

021372S

Genistein, 99%, synthetic

Acros Organics BVBA

AOB9503800

4,5,7-Trihydroxyisoflavone

Manchester Organics Limited

X22563

4',5,7-Trihydroxyisoflavone

Capot Chemical Co., Ltd.

9852

4',5,7-Trihydroxyisoflavone

Iris Biotech GmbH

LS-1032

4',5,7-Trihydroxyisoflavone

Shandong SanYoung Industry Co., Ltd

SSI18907560

Genistein ( 4',5,7-Trihydroxyisoflavone)

Medibro Corporation Limited

MCL332113284

4H-1-benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-

Angene International Limited

AGN-PC-00GV2H

4',5,7-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Shanghai UCHEM Inc.

UCHEM-4546

Prices & Availability

Data is processed

Properties for Genistein

Molecular Weight:

270.24 g·mol−1

Density:

1.55 g/cm³

Melting point:

297-298 °C

Boiling point:

555.51° C at 760 mmHg

Solubility:

DMSO: soluble

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice

Hazard Classes:

irritant

Hazard Symbols:

Xi, Xn

Storage temperature :

-20°C

Alternative Distributors of [Genistein]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified