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Geneticin (G418) Sulfate

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Formula: C20H40N4O10.2(H2SO4)
CAS: 108321-42-2
search Element: geneticin sulfate g418
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Identification

Structural Formula
Geneticin (G418) Sulfate
CAS:
108321-42-2
EINECS:
Molecular Formula:
C20H40N4O10.2(H2SO4)
MDL:
MFCD00058314
SMILES:
C[C@H]([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)O)O)O.OS(=O)(=O)O.OS(=O)(=O)O
Synonym:
g418 sulfate ; g-418.sulfatesolid ; geneticin sulfate. ; g-418,geneticin ; geneticinedisulfate ; geneticin ; g418 solution ; g 418 ; g-418 sulphate ; 620u/mg


Description

Geneticin (G418) Sulfate is an aminoglycoside antibiotic that has originally been derived from Micromonospora rhodoranga NRRL 5326. This compound has been shown to cause a bypass of nonsense mutations during translation. Experiments have shown that geneticin sulfate inhibits the incorporation of amino acids into protein and can destroy fibroblasts. Mechanistic studies suggest that this agent affects the 80S ribosome and inhibits the elongation cycle. Further studies report that geneticin sulfate is highly active against amoebae, protozoa, tapeworm, and pinworm exposed murine cells.


Suppliers

Santa Cruz Biotechnology, Inc.
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Prices & Availability




Data is processed


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Properties for Geneticin (G418) Sulfate

Molecular Weight:
692.71 g·mol−1
Boiling point:
1012.1 °C at 760 mmHg (Predicted)
Solubility:
H2O: 50 mg/mL
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R42/43 - May cause sensitization by inhalation and skin contact
Safety Codes:
S22 - Do not breathe dust
S23 - Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer)
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
Xn, Xi
Hazard symbol Xn Hazard symbol Xi
Storage temperature :
2-8°C
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Alternative Distributors of [Geneticin (G418) Sulfate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

World Biopharma Group Limited / World (Jiangsu) Industry Co.,Ltd | World Industry Co. Ltd., (Factory) | Lanospharma Laboratories Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Shanghai GenJoy Chemical Technology Co., Ltd.

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