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Gemcitabine hydrochloride

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Formula: C9H11F2N3O4.HCl
CAS: 122111-03-9

Identification

Structural Formula
Gemcitabine hydrochloride
CAS:
122111-03-9
EINECS:
Molecular Formula:
C9H11F2N3O4.HCl
MDL:
MFCD01735988
SMILES:
C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl
Synonym:
gemcitera ; dfdc ; dfdcyd ; gemzar ; ddfc ; gemsar ; gecitabine ; gemcitabine hcl ; gemzar (lilly) ; ly188011


Description

Gemcitabine Hydrochloride is a deoxycytidine analog with cytotoxic effects. Gemcitabine Hydrochloride inhibits DNA synthesis and induces apoptosis through inhibition of ribonucleotide reductase (R1 and R2).


Suppliers

Autech Industry Co.,Limited
AIC13505400
Ambeed, Inc.
A309564
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI345013800
H&Z Industry Co.,Ltd
HIC10004000
Shandong SanYoung Industry Co., Ltd
SSI17507000
Chemlyte Solutions
CS9002700
General Intermediates of Canada, Inc.
GIOC18509250
BoomKing Industrial Co.,Limited
BIC15506200
Shanghai Mintchem Development Co., Ltd.
SMD19507800
Xiamen Equation Chemical Co.,Ltd
XECC16008000
Aecochem Corp.
AC7002100
Hangzhou Keying Chem Co., Ltd.
HKC15006000
Wanko Chemical Co., Ltd.
WC12003600
Sigma-Aldrich International GmbH
SI16004800
scienTEST - bioKEMIX GmbH
S-B12505000
Finetech Industry Limited
FIL12505000
Acinopeptide Co., Ltd.
A11002200
Hefei Hirisun Pharmatech Co., Ltd
HR013322
CM Fine Chemicals
CFC8503400
AK Scientific, Inc.
AS9502850
Xingrui Industry Co., Limited
XIL14505800
BOC Sciences
BS6001800
Leap Chem Co., Ltd
LC9002700
Santa Cruz Biotechnology, Inc.
204763
Dayang Chem (Hangzhou) Co.,Ltd.
DC15506200
Chemos GmbH & Co. KG
CC10003000
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Prices & Availability




Data is processed


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Properties for Gemcitabine hydrochloride

Molecular Weight:
299.66 g·mol−1
Melting point:
>250 °C dec.
Boiling point:
482.7° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (100 mM), methanol (slightly), DMSO (50 mM), and acetone. Insoluble in ethanol.
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Hazard Statements

GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R21 - Harmful in contact with skin
R36/38 - Irritating to eyes and skin
R46 - May cause inheritable genetic damage
R62 - Possible risk of impaired fertility
R63 - Possible risk of harm to the unborn child
Safety Codes:
S25 - Avoid contact with eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
Xn, Xi
Hazard symbol Xn Hazard symbol Xi
Storage temperature :
Desiccate at +4 °C
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Alternative Distributors of [Gemcitabine hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Inter-Chemical Ltd. | YHEDC (Yi Heng Enterprises Development Co.) | Molekula GmbH | Qventas, Inc. | Dalian Richon Chem Co., Ltd. | Hallochem Pharma Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | Hangzhou Onicon Chemical Co., Ltd. | Ningbo Yuanfang Biochemicals Co., Ltd. | Ningbo Highpharm Chem&Indu Co., Ltd. | Evershine Chemical Co.,Ltd. | Benro Internatinal Co., Linc | Hangzhou Sida Organic Chemical Co., Ltd. | Melone Pharmaceutical Co., Ltd. | Afine Chemicals Limited | Xiang Ding Chemical International Co., Ltd | Qichun QiLong Chemical Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Jiangsu Honghui Pharmaceutical Co., Ltd. | Xingcheng Chempharm Co., Ltd. | Taizhou Huading Chemical Co., Ltd. | Duheng Bio-tech Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Originchem Co., Ltd. | Ningbo Medicn Pharmaceutical Co., Ltd. | Shanghai Henghe Pharma-Tech Co., Ltd. | Longschem Co., Ltd. | Beijing Lunarsun Pharmaceutical Co. Ltd. | New Dragon Industrial Co., Ltd | Zhejiang Esun Chemical Co., Ltd. | ShangHai Biochempartner Co., Ltd. | Zibo Panxin Pharmaceutical Co., Ltd. | Shanghai Yongyi Biotechnology Co., Ltd. | Discovery Fine Chemicals Limited | Hangzhou Hysen Pharma Co., Ltd. | Shanghai Yingxuan Chempharm Co., Ltd. | Hubei Honch Pharmaceutical Co., Ltd. | Taizhou Bolon Pharmachem Co.,Ltd.. / Bolon Pharm & Chem Co., Ltd. | Shanghai AOKChem Group Limited | JingZhou WinChem Pharm.&Chem. Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Shanghai Marketing Center of Yangzhou Princechem Co., Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Lanospharma Laboratories Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | TCS INDUSTRY LTD. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | Nanjing Dernor Pharmaceutical Technology Co., Ltd. | Nantong Wanrong International Trading Co., Ltd. | Hangzhou Holypharm Biotech Co., Ltd. | East Chemical Industry Co., Ltd. | Kairer Chengdu Pharmaceutical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | API Vanguard | Pharmfar Co., Ltd. | Watson International Ltd | Aopharm | BOC Sciences | Hangzhou Ocean Chemical Co., Ltd. | Mei Le Shi Limited | All Right Chemical Co., Ltd. | WuHan Rison Trading Co.,Ltd. | Jinan Haohua Industry Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Angel Synthesis Co., Ltd | scienTEST | Clearsynth Canada INC. | Intatrade Chemicals GmbH | Amadis Chemical Co., Ltd. | Haihang Industry Co., Ltd.

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