Ganciclovir | CAS 82410-32-0 | Chemical-Suppliers

Element: ganciclovir

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C-S » Chemicals » ganciclovir-PX68559

Identification

Ganciclovir

CAS:

82410-32-0

EINECS:

Molecular Formula:

C₉H₁₃N₅O₄

MDL:

MFCD00870588

SMILES:

C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N

Synonym:

Description

Ganciclovir is a nucleoside analog structurally related to Acyclovir that acts as a prodrug activated by phosphorylation. Ganciclovir has been used in the study of “suicide” gene therapy in cancer research, where upon expression of a viral suicide gene encoding herpes simplex virus, thymidine kinase (TK), the non-toxic prodrug ganciclovir, is converted to an active phosphorylated analog that can be incorporated into the DNA of replicating eukaryotic cells, causing death of the malignant dividing cell. Causes an irreversible cell cycle arrest at the G2/M checkpoint. Ganciclovir has also been used to study the loss of telomeres and to evaluate sensitivity of viruses to antiviral agents.

Suppliers

Shandong SanYoung Industry Co., Ltd

SSI3851540

Chemlyte Solutions

CS198594

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI7593036

Shandong Ench Chemical Co.,Ltd

SECC3301650

H&Z Industry Co.,Ltd

HIC220880

Autech Industry Co.,Limited

AIC2971188

Indofine Chemical Co, Inc.

Bio-998

EXCELLA GmbH

E132264

Hangzhou Verychem Science & Technology Co., Ltd.

HVST5282640

Xiamen Equation Chemical Co.,Ltd

XECC3521760

Hangzhou Zhongqi Chem Co., Ltd

HZC3301320

CSNpharm, Inc.

CSN12977

Hangzhou Lingrui Chemical Co., Ltd.

HLC3851540

Sigma-Aldrich International GmbH

SI3521056

Finetech Industry Limited

FIL2751100

Pharmacore Co., Limited

PL253759

AK Scientific, Inc.

AS209627

Xingrui Industry Co., Limited

XIL3191276

Leap Chem Co., Ltd

LC198594

Santa Cruz Biotechnology, Inc.

203963

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BLD Pharmatech Ltd

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Prices & Availability

Data is processed

Properties for Ganciclovir

Molecular Weight:

255.23 g·mol−1

Density:

1.81 g/cm3

Melting point:

250 °C

Boiling point:

675 °C at 760 mmHg

Flash point:

362 °C

Solubility:

0.1 M HCl: 10 mg/mL

Physical Description:

white powder

Hazard Statements

GHS08
Health hazard

Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A, 1B, 2
Carcinogenicity, categories 1A, 1B, 2
Reproductive toxicity, categories 1A, 1B, 2
Specific target organ toxicity following single exposure, categories 1, 2
Specific target organ toxicity following repeated exposure, categories 1, 2
Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:

R46 - May cause inheritable genetic damage
R60 - May impair fertility
R61 - May cause harm to the unborn child

Safety Codes:

S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use

Hazard Symbols:

Storage temperature :

2-8°C

Alternative Distributors of [Ganciclovir]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified