γ-Secretase Inhibitor XVI | CAS 208255-51-0

Element: inhibitor secretase gamma

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C-S » Chemicals » gamma-secretase-inhibitor-xvi-PX68697

Identification

γ-Secretase Inhibitor XVI

CAS:

208255-51-0

EINECS:

Molecular Formula:

C₂₀H₂₀F₂N₂O₄

MDL:

MFCD04974586

SMILES:

C[C@@H](C(=O)N[C@@H](C1=CC=CC=C1)C(=O)OC)NC(=O)CC2=CC(=CC(=C2)F)F

Synonym:

dapm ; ?-secretase inhibitor xvi ; gamma-secretase inhibitor xvi ; 3,5-difluorophenylacetyl-ala-phg-ome ; n-[n-3,5-difluorophenacetyl]-l-alanyl-s-phenylglycine methyl ester

Description

γ-Secretase Inhibitor XVI A cell-permeable γ-secretase inhibitor with anti-aggregation properties. The compound prevents early Aβ oligomerization by selectively blocking the Aβ dimer and Aβ trimer formation.