Y-27632, free base | CAS 146986-50-7

Element: 27632 base free

Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » free-base-PX17503

Identification

Y-27632, free base

CAS:

146986-50-7

EINECS:

Molecular Formula:

C₁₄H₂₁N₃O.2HCl

MDL:

MFCD03490488

SMILES:

C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N

Synonym:

Description

Y-27632, free base is the free base form of Y-27632 dihydrochloride, a selective Rho-kinase inhibitor, which suppresses cholinergic nerve-mediated contractions. In addition, studies show that Y-27632 increases the release of neurotransmitters from cholinergic nerves. Studies conducted on smooth muscle preparations suggest that Y-27632 suppresses nerve-mediated contractile responses stimulated by acetylcholine and noradrenaline. Furthermore, studies on lung tissue damage in rats suggest that Y-27632 can restore the damage caused by oleic acid by inhibition of ROCK-1 and ROCK-2. Y-27632 also inhibits protein kinase C related kinase, PRK2.

Suppliers

Santa Cruz Biotechnology, Inc.

3536

Get Quick Quote

CAS equal suppliers

Y-27632

ShangHai Biochempartner Co., Ltd.

BCP01863

Y-27632

Pharmacore Co., Limited

PL161483

Y-27632

Ambeed, Inc.

A112358

Y-27632

Excenen Pharmatech Co., Ltd.

EX-A423

Y-27632

CSNpharm, Inc.

CSN12226

Y-27632

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI4831932

Y-27632

Aea.ltd

A4998

Y-27632

Chemlyte Solutions

CS126378

Y-27632 dihydrochloride

SYNCHEM UG & Co. KG

un229

Y-27632 dihydrochloride

Chemieliva Pharmaceutical Co., Ltd.

CP16104830

Y-27632 dihydrochloride

Leap Chem Co., Ltd

LC8282484

Y-27632 dihydrochloride

Hefei Hirisun Pharmatech Co., Ltd

HR060244

Y-27632 Dihydrochloride

Jiwan Pharmaceutical Technology Co., Ltd.

JPT18867544

Y-27632 dihydrochloride

SYNCHEM UG & Co. KG

SUC8743496

Y-27632 dihydrochloride

Finetech Industry Limited

FIL11504600

Y-27632 dihydrochloride

Xingrui Industry Co., Limited

XIL13345336

Y-27632 dihydrochloride

Amadis Chemical Company Limited

ACCL14267130

Cyclohexanecarboxamide, 4-[(1r)-1-aminoethyl]-n-4-pyridinyl-, trans-

Angene International Limited

AGN-PC-0O3F2M

Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, trans-

CM Fine Chemicals

CFC924836992

Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, trans-

Sirius Fine Chemicals SiChem GmbH

SC-0048

(+)-(R)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride

Pt. Sarana Bela Nusa

PSBN1476073800

Prices & Availability

Data is processed

Properties for Y-27632, free base

Molecular Weight:

338.28025 g·mol−1

Solubility:

Soluble in water (14 mg/mL), ethanol (~5 mg/mL), DMSO (~20 mg/mL), DMF (~30 mg/mL), PBS, pH 7.2 (~10 mg/mL), and methanol (25 mg/mL).

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Alternative Distributors of [Y-27632, free base]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Great Chemical Co., Ltd. | Shanghai Sun-shine Chemical Technology Co., Ltd. | ChengDu KaiXin Technology Development Co., Ltd. | BOC Sciences | Jinan Haohua Industry Co., Ltd.