(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3,3-dimethylpentanoic acid

CAS: 1310680-40-0

Element: dimethylpentanoic carbonylamino fluoren methoxy acid

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C-S » Chemicals » fluoren-methoxy-carbonylamino-dimethylpentanoic-acid-PX1830677

Identification

Structural Formula

(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3,3-dimethylpentanoic acid

CAS:

1310680-40-0

EINECS:

Molecular Formula:

MDL:

Synonym:

Description

beta,beta-Dimethylation of amino acids stabilizes appropriate peptides towards digestion by proteases. Reference: Total synthesis of the large non-ribosomal peptide polytheonamide B; Masayuki Inoue, Naoki Shinohara, Shintaro Tanabe, Tomoaki Takahashi, Ken Okura, Hiroaki Itoh, Yuki Mizoguchi, Maiko Iida, Nayoung Lee and Shigeru Matsuoka; Nature Chem. 2010; 2: 281-285. DOI: 10.1038/nchem.554.

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Fmoc-beta,beta-diMe-D-pentanoic acid

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