Felodipine | CAS 72509-76-3 | Chemical-Suppliers

Element: felodipine

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C-S » Chemicals » felodipine-PX66169

Identification

Felodipine

CAS:

72509-76-3

EINECS:

Molecular Formula:

C₁₈H₁₉Cl₂NO₄

MDL:

MFCD00868316

SMILES:

CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C

Synonym:

munobal ; modip ; cgh-869 ; h154/82 ; agon ; splendil ; spendil ; plendil ; p|endil ; hydac

Description

Felodipine is a 1,4-dihydropyridine small molecule antagonist and calcium channel protein inhibitor. Antagonism of the vascular L-type (long-lasting) calcium channel decreases intracellular calcium concentration, softening the tone of vascular tissue and decreasing the peripheral resistance upon the blood stream, effectively decreasing systemic arterial blood pressure without affecting myocardial contractility. Felodipine is described to inhibit cytokine-induced NO and superoxide production as well as cytokine-induced NO synthase (NOS) mRNA induction, and is suggested to act as a scavenger of superoxide and not an inhibitor of inducible NOS induction. This indicates that Felodipine further protects the vasculature against endogenous free radical generation during inflammatory responses.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6902760

H&Z Industry Co.,Ltd

HIC200800

Autech Industry Co.,Limited

AIC2701080

Chemlyte Solutions

CS180540

Ambeed, Inc.

A268185

Acanthus Research Inc.

AR220660

Biddle Sawyer Corp.

BSC190760

Kum Yang Co., Ltd.

KY180540

Alfa (A Johnson Matthey Company)

A320960

Xiamen Equation Chemical Co.,Ltd

XECC3201600

Aecochem Corp.

AC140420

CSNpharm, Inc.

CSN17326

Wanko Chemical Co., Ltd.

WC240720

Sigma-Aldrich International GmbH

SI320960

scienTEST - bioKEMIX GmbH

S-B2501000

Hefei Hirisun Pharmatech Co., Ltd

HR130469

AK Scientific, Inc.

AS190570

Simagchem Corporation

SC210630

Xingrui Industry Co., Limited

XIL2901160

Capot Chemical Co., Ltd.

15919

BOC Sciences

BS120360

Leap Chem Co., Ltd

LC180540

Santa Cruz Biotechnology, Inc.

201483

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CAS equal suppliers

rac Felodipine-d3

Santa Cruz Biotechnology, Inc.

sc-219831

3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

BLD Pharmatech Ltd

BP1296038880

3-ethyl 5-Methyl 4-(2',3'-dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylate

Pharmacore Co., Limited

PL1904457132

Prices & Availability

Data is processed

Properties for Felodipine

Molecular Weight:

384.25 g·mol−1

Density:

1.28

Melting point:

142-145 °C

Boiling point:

471.52° C at 760 mmHg

Solubility:

DMSO: 28 mg/mL

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed

Safety Codes:

S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

Store at +4 °C

Alternative Distributors of [Felodipine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified