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FAAH Inhibitor II

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Formula: C20H22N2O3
CAS: 546141-08-6
search Element: inhibitor faah
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Identification

Structural Formula
FAAH Inhibitor II
CAS:
546141-08-6
EINECS:
Molecular Formula:
C20H22N2O3
MDL:
MFCD05863934
SMILES:
O=C(NC1CCCCC1)Oc1cccc(c1)c1cccc(c1)C(=O)N
Synonym:
kds 4103 ; urb 597, >=98% ; urb597 ; 3'-carbamoyl-[1,1'-biphenyl]-3-yl cyclohexylcarbamate ; (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate ; apd597(urb597) ; 3'-carbamoyl-biphenyl-3-yl-cyclohexylcarbamate ; cyclohexylcarbamic acid 3'-carbamoyl-biphenyl-3-yl ester ; faah inhibitor ii ; 3-(3-carbamoylphenyl)phenyl n-cyclohexylcarbamate


Description

FAAH Inhibitor II is a cell-permeable carbamate compound that acts as a potent, selective, and irreversible inhibitor of FAAH (fatty acid amide hydrolase; IC50 = 4.6 nM in brain membranes). Shown to block anandamide breakdown in rat cortical neurons (IC50 = 500 pM) and modulate anxiety in rats (ID50 = 0.15 mg/Kg). Does not affect the activities of several serine hydrolases (IC50 > 30 μM), including AChE (acetylcholinesterase), BCh (butyrylcholinesterase) and MGL (monoglyceride lipase). FAAH Inhibitor II does not interfere with the binding of anandamide to cannabinoid receptors CB1 and CB2 (IC50 > 100 μM), as well as several ion-channels and neurotransmitter transporters.


Suppliers

Santa Cruz Biotechnology, Inc.
202605
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Prices & Availability




Data is processed


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Properties for FAAH Inhibitor II

Molecular Weight:
338.4 g·mol−1
Density:
1.23
Melting point:
226.82° C (Predicted)
Boiling point:
533.17° C at 760 mmHg (Predicted)
Solubility:
DMSO: ~14 mg/mL, soluble
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Safety & Transport Information

Risk Codes:
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S60 - This material and its container must be disposed of as hazardous waste
S61 - Avoid release to the environment. Refer to special instructions/safety data sheet
Hazard Symbols:
N
Hazard symbol N
Storage temperature :
2-8°C
RID/ADR certification :
UN 3077 9 / PG 3
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Alternative Distributors of [FAAH Inhibitor II]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Wanko Chemical Co., Ltd.

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