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Etifoxine

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Formula: C17H17 Cl N2 O
CAS: 21715-46-8
search Element: etifoxine
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Identification

Structural Formula
Etifoxine
CAS:
21715-46-8
EINECS:
Molecular Formula:
C17H17 Cl N2 O
MDL:
SMILES:
CCNC1=NC2=C(C=C(C=C2)Cl)C(O1)(C)C3=CC=CC=C3
Synonym:
hoe-36-801 ; 4h-3,1-benzoxazin-2-amine,6-chloro-n-ethyl-4-methyl-4-phenyl- ; 2-ethylamino-6-chloro-4-methyl-4-phenyl-4h-3,1-benzoxazine ; 4h-3,1-benzoxazine,6-chloro-2-(ethylamino)-4-methyl-4-phenyl- (8ci) ; 6-chloro-2-ethylamino-4-methyl-4-phenyl-4h-3,1-benzoxazine ; hoe 36-801 ; etifoxin ; etifoxine ; hoe-36801 ; 36-801 ; etafenoxine


Description

Etifoxine is a non-benzodiazepine modulator of GABAergic synaptic transmission described to produce anxiolytic effects. Etifoxine is demonstrated to potentiate GABAA receptor function in cultured neurons through interaction at the β subunit of the receptor, and is shown to evoke a chloride current in the absence of GABA and to enhance GABA-activated currents.


Suppliers

Santa Cruz Biotechnology, Inc.
211491
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CAS equal suppliers

2-Ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine
Leap Chem Co., Ltd
LC626418792

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Properties for Etifoxine

Molecular Weight:
300.787 g·mol−1
Density:
1.2 g/cm3
Melting point:
90-92°C
Boiling point:
421.2°C at 760 mmHg
Flash point:
208.5°C
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Safety & Transport Information

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. A tranquilizer. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
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Alternative Distributors of [Etifoxine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC. | Wanko Chemical Co., Ltd.

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MSDS:
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