N2-Ethyl-2'-deoxyguanosine | CAS 101803-03-6

Element: deoxyguanosine ethyl

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C-S » Chemicals » ethyl-deoxyguanosine-PX46742

Identification

N2-Ethyl-2'-deoxyguanosine

CAS:

101803-03-6

EINECS:

Molecular Formula:

C₁₂H₁₇N₅O₄

MDL:

SMILES:

CCNC1=NC(=O)C2=C(N1)N(C=N2)[C@H]3C[C@@H]([C@H](O3)CO)O

Synonym:

n2-et-dg ; 2'-deoxy-n-ethylguanosine ; n2-ethyl-2'-deoxyguanosine

Description

Adduct between DNA and acetaldehyde, the first metabolite of ethanol, that strongly blocks transcription by RNAPs (including RNAPII, both mammalian and yeast, E. coli RNAP, and T7 RNAP).

Suppliers

Santa Cruz Biotechnology, Inc.

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Prices & Availability

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Properties for N2-Ethyl-2'-deoxyguanosine

Molecular Weight:

295.29 g·mol−1

Solubility:

Soluble in water: >5 mg/mL

Safety & Transport Information

Risk Codes:

R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
R33 - Danger of cumulative effects
R40 - Limited evidence of a carcinogenic effect

Safety Codes:

S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

T+