5-[[4-(ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid | CAS 78028-01-0

Element: ethoxycarbonyl benzeneacetic hydroxy phenyl acid

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C-S » Chemicals » ethoxycarbonyl-phenyl-azo-hydroxy-benzeneacetic-acid-PX74597

Identification

5-[[4-(ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid

CAS:

78028-01-0

EINECS:

Molecular Formula:

C_₁₇H_₁₆N_₂O_₅

MDL:

SMILES:

CCOC(=O)c1ccc(cc1)/N=N/c2ccc(c(c2)CC(=O)O)O

Synonym:

CAY10397

Description

5-[[4-(ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid is a selective inhibitor of 15-hydroxy PGDH (IC₅₀ ~ 10 µM) which acts to prolong the lifetime and activity of endogenously produced prostaglandins in cell cultures. 5-[[4-(ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid has also been shown to oxidize the 15-hydroxyl group and hydrogenate the 13,14-double bond on prostaglandins, producing 13,14-dihydro-15 keto metabolites with greatly reduced biological activity.

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Properties for 5-[[4-(ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid

Molecular Weight:

328.32 g·mol−1

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Alternative Distributors of [5-[[4-(ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid]

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