1,N6-Ethenoadenosine-5'-diphosphate

1,N6-Ethenoadenosine-5'-diphosphate is an analog of ADP that has been derivatized with an ethene moiety attached to the N-1 and the exocyclic amine N-6 positions. 1,N6-Ethenoadenosine-5'-diphosphate was described to be useful in NMR studies of ADP binding at the active site of creatine kinase, where the nuclear Overhauser effect of the H-2 proton on ADP was used to identify the amino acid residue binding ADP. The N-1 and N-6 nitrogens of 1,N6-Ethenoadenosine-5'-diphosphate are unavailable for hydrogen bonding which made the compound useful in identifying these H-2 proton couplings more easily. 1,N6-Ethenoadenosine-5'-diphosphate may be useful in other studies of ADP interactions.