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D-erythro-N,N-Dimethylsphingosine

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Formula: C20H41NO2
CAS: 119567-63-4
search Element: dimethylsphingosine erythro
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Identification

Structural Formula
D-erythro-N,N-Dimethylsphingosine
CAS:
119567-63-4
EINECS:
Molecular Formula:
C20H41NO2
MDL:
SMILES:
CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)N(C)C)O
Synonym:
n,n-dimethyl-d-erythro-sphingosine ; dimethyl-d-erythro-sphingosine ; n,n-dimethyl-d-erthyro-sphingosine ; d-erythro-sphingosine, n,n-dimethyl- ; n,n-dimethylsphingosine ; n,n-dimethylsphingenine ; sphingosine, n,n-dimethyl ; d-erythro-n,n-dimethylsphingosine ; n,n-dimethylsphingosine, d-erythro ; dimethylsphingosine


Description

D-erythro-N,N-Dimethylsphingosine inhibits SphK (sphingosine kinase), blocking the conversion of sphingosine to sphingosine-1 phosphate. It is an endogenous compound produced via ceramide catabolism. D-erythro-N,N-Dimethylsphingosine is capable of producing EGF-like activity in vitro without the presence of any EFG-2 by stereospecifically inducing EGF receptor autophosphorylation. D-erythro-N,N-Dimethylsphingosine has been shown to inhibit PKC (protein kinase C), enhance src-kinase activity, and induce apoptosis.


Suppliers

Santa Cruz Biotechnology, Inc.
201373
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CAS equal suppliers

N,N-Dimethylsphingosine
Dayang Chem (Hangzhou) Co.,Ltd.
DC14265704

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Properties for D-erythro-N,N-Dimethylsphingosine

Molecular Weight:
327.55 g·mol−1
Flash point:
14 °C
Solubility:
Soluble in ethanol (25 mg/ml), DMSO (25 mg/ml), methanol, and Chloroform.
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S7 - Keep container tightly closed
Hazard Symbols:
F
Hazard symbol F
Storage temperature :
-20°C
RID/ADR certification :
UN 1170 3 / PG 2
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Alternative Distributors of [D-erythro-N,N-Dimethylsphingosine]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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