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Erlotinib Hydrochloride

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Formula: C22H23N3O4.HCl
CAS: 183319-69-9
search Element: hydrochloride erlotinib
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Identification

Structural Formula
Erlotinib Hydrochloride
CAS:
183319-69-9
EINECS:
Molecular Formula:
C22H23N3O4.HCl
MDL:
MFCD07781272
SMILES:
COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)C#C)OCCOC.Cl
Synonym:
erlotinib hcl ; erlotinib, os-774 ; erlotinib-d6 hcl ; erlotonid hcl ; osi 774 ; erlotinib hcl salt ; tarceva ; nsc 718781) hcl ; nsc718781 ; cp 358774


Description

Erlotinib Hydrochloride is a small molecule inhibitor of the EGFR/HER-1 (human epidermal growth factor receptor) tyrosine kinase. Overexpression of the EGFR is present in many carcinomas, and inhibition of the activating kinase by Erlotinib provides a chemical intervention upon these systems. The inhibition of this tyrosine kinase effectively blocks EGFR activity but does not suppress tumor growth. When combined with 3,3'-diindolylmethane, efficacy against tumor proliferation was demonstrated.


Suppliers

Shandong Minglang Chemical Co., Ltd
SMC16106440
+
Refine Chemical Co.,Ltd.
RCC11044416
+
H&Z Industry Co.,Ltd
HIC9203680
+
Autech Industry Co.,Limited
AIC12424968
+
Ambeed, Inc.
A154463
+
Wuhan PharmChem Co., LTD.
WP11503450
+
OPQ Chemical Co., Ltd
OC9662898
+
Shandong SanYoung Industry Co., Ltd
SSI16106440
+
Aozeal Certified Standards (AOCS), Inc.
E0020.00
+
Nantong Xindao Biotech Ltd
NXB11964784
+
Chemlyte Solutions
CS8282484
+
FUDI Chemical Co. Ltd.
FCC10124048
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI317412696
+
Arcadia Biotechnology
AB9662898
+
Xiamen Equation Chemical Co.,Ltd
XECC14727360
+
Finetech Industry Limited
FIL11504600
+
AK Scientific, Inc.
AS8742622
+
Xingrui Industry Co., Limited
XIL13345336
+
Capot Chemical Co., Ltd.
30292
+
BOC Sciences
BS5521656
+
Amadis Chemical Company Limited
ACCL14267130
+
Santa Cruz Biotechnology, Inc.
202154
Dayang Chem (Hangzhou) Co.,Ltd.
DC14265704
+
Get Quick Quote

CAS equal suppliers

Tarceva
Huateng Pharmaceutical Co.,Ltd
80008700
Erlotinib Hcl
Hangzhou J&H Chemical Co., Ltd.
HJC8063224
Erlotinib HCl
Exim Corporation
EC4161248
Erlotinib HCl
ShangHai Biochempartner Co., Ltd.
BCP02600
Erlotinib HCl
Excenen Pharmatech Co., Ltd.
EX-A064
Erlotinib HCl
CSNpharm, Inc.
CSN16725
Erlotinib HCl (OSI-744)
CM Fine Chemicals
CFC11734692
Erlotinib HCl (OSI-744)
Chemieliva Pharmaceutical Co., Ltd.
CP24157245
Erlotinib HCl (OSI-744)
Leap Chem Co., Ltd
LC12423726
Erlotinib HCl (OSI-744)
Zhejiang Hongxin Chemical
ZHC17256900
Erlotinib HCl (OSI-744)
LGM Pharma
LP6902070
Erlotinib HCl (OSI-744)
Hangzhou Lingrui Chemical Co., Ltd.
HLC24159660
Erlotinib HCl (OSI-744)
Wanko Chemical Co., Ltd.
WC16564968
erlotinib hydrochloride salt
Indofine Chemical Co, Inc.
Bio-805
N-(3-Ethynylphenyl)-[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine hydrochloride
BLD Pharmatech Ltd
BP1296038880

Prices & Availability




Data is processed


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Properties for Erlotinib Hydrochloride

Molecular Weight:
429.9 g·mol−1
Melting point:
223-225 °C
Solubility:
Soluble in DMSO (3 mg/ml), methanol (sparingly), water (<1 mg/ml), and ethanol (<1 mg/ml).
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Erlotinib Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

China Risesun Group Co., Ltd. | YHEDC (Yi Heng Enterprises Development Co.) | Xiang Ding Chemical International Co., Ltd | Qichun QiLong Chemical Co., Ltd. | Shanghai Henghe Pharma-Tech Co., Ltd. | Pharmasi Chemicals Co., Ltd. | Kouting Chemical Co., Ltd. | Zouping Mingxing Chemical Co., Ltd. | Melone Pharmaceutical Co., Ltd. | Zhejiang Esun Chemical Co., Ltd. | Conier Chem & Pharma Ltd | ShangHai Biochempartner Co., Ltd. | All Right Chemical Co., Ltd. | ZhiYu Biotechnology Co., Ltd. | Shanghai Yongyi Biotechnology Co., Ltd. | Shanghai Yingxuan Chempharm Co., Ltd. | Shanghai AOKChem Group Limited | Shanghai Richem International Co., Ltd. | TRUST&WE Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai ChemVia Co., Ltd | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Nanjing CHICO Pharmaceutical Co., Ltd. | Evershine Chemical Co.,Ltd. | Shanghai Marketing Center of Yangzhou Princechem Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Wuhan Sunrise Technology Development Company Ltd. | Rosewell Industry Co., Ltd. | TCS INDUSTRY LTD. | Win-Win Chemical Co., Limited | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | Nanjing Dernor Pharmaceutical Technology Co., Ltd. | 3Way Pharm Inc. | Shanghai Insight Chemicals Co., Ltd. | Hangzhou Holypharm Biotech Co., Ltd. | East Chemical Industry Co., Ltd. | API Vanguard | ChengDu KaiXin Technology Development Co., Ltd. | Discovery Fine Chemicals Limited | Cfm Oskar Tropitzsch GmbH | Pharmfar Co., Ltd. | Watson International Ltd | Aopharm | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Shanxi Jinjin Chemical Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Clearsynth Canada INC. | Haihang Industry Co., Ltd. | Kinbester Co., Ltd.

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