2-(14,15-Epoxyeicosatrienoyl) Glycerol | CAS 848667-56-1

Element: epoxyeicosatrienoyl glycerol

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C-S » Chemicals » epoxyeicosatrienoyl-glycerol-PX66506

Identification

2-(14,15-Epoxyeicosatrienoyl) Glycerol

CAS:

848667-56-1

EINECS:

Molecular Formula:

C₂₃H₃₈O₅

MDL:

MFCD10567087

SMILES:

CCCCCC1C(O1)CC=CCC=CCC=CCCCC(=O)OC(CO)CO

Synonym:

2-14,15-eg ; 5,8,11-tridecatrienoic acid, 13-(3-pentyloxiranyl)-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5z,8z,11z)- ; 2-(14,15-epoxyeicosatrienoyl) glycerol

Description

2-(14,15-Epoxyeicosatrienoyl) Glycerol (2-14,15-EG) is a novel CYP450 metabolite of 2-Arachidonoyl glycerol (2-AG) in the kidney. 2-14,15-EG is a potent mitogen for renal epithelial cells, increasing DNA synthesis in LLCPKcl4 cells at concentrations as low as 100 nM and doubling cell proliferation rates at 1 μM. In these cells, 2-14,15-EG activates the metalloprotease ADAM17 (TACE), which cleaves proTGF-α and releases TGF-α as a ligand that initiates the EGFR-ERK signalling pathway.

Suppliers

Santa Cruz Biotechnology, Inc.

205073

Dayang Chem (Hangzhou) Co.,Ltd.

DC353414136

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Prices & Availability

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Properties for 2-(14,15-Epoxyeicosatrienoyl) Glycerol

Molecular Weight:

394.5 g·mol−1

Boiling point:

84° C

Solubility:

Soluble in DMSO (~10 mg/ml), DMF (~10 mg/ml), aqueous solutions, and ethanol (~50 mg/ml).

Safety & Transport Information

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Alternative Distributors of [2-(14,15-Epoxyeicosatrienoyl) Glycerol]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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