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Entacapone

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Formula: C14H15N3O5
CAS: 130929-57-6
search Element: entacapone

Identification

Structural Formula
Entacapone
CAS:
130929-57-6
EINECS:
Molecular Formula:
C14H15N3O5
MDL:
MFCD00866580
SMILES:
CCN(CC)C(=O)C(C#N)=CC1=CC(O)=C(O)C(=C1)[N+]([O-])=O
Synonym:
comtes ; comtan ; entacapone f·s ; (e)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-n,n-diethylacrylamide ; entacapone (150 mg) ; comtess ; or-611 ; (e)-2-cyano-3-(3 , 4-dihydroxy-5-nitrophenyl)-n , n-diethyl-2-pmpenamide ; (2e)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-n,n-diethylprop-2-enamide ; entacapone


Description

Entacapone is (E)-Isomer of Entacapone polymorphic form A. Peripherally acting inhibitor of COMT (catechol-O-methyl transferase), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.


Suppliers

FUDI Chemical Co. Ltd.
FCC220880
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
H&Z Industry Co.,Ltd
HIC200800
Chemlyte Solutions
CS180540
Ambeed, Inc.
A102154
Arcadia Biotechnology
AB210630
Xiamen Equation Chemical Co.,Ltd
XECC3201600
Sancai Industry Co.,Ltd.
SIC240960
CSNpharm, Inc.
CSN17052
Hangzhou Lingrui Chemical Co., Ltd.
HLC3501400
Wanko Chemical Co., Ltd.
WC240720
Sigma-Aldrich International GmbH
SI320960
Carbone Scientific Co., Ltd.
CS280840
Pharmacore Co., Limited
PL230690
Hefei Hirisun Pharmatech Co., Ltd
HR012286
Xingrui Industry Co., Limited
XIL2901160
BOC Sciences
BS120360
Leap Chem Co., Ltd
LC180540
Santa Cruz Biotechnology, Inc.
218315
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CAS equal suppliers

(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide
BLD Pharmatech Ltd
BP936028080

Prices & Availability




Data is processed


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Properties for Entacapone

Molecular Weight:
305.29 g·mol−1
Density:
~1.4 g/cm3 (Predicted)
Melting point:
162-1630C
Boiling point:
~526.6° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (61 mg/ml at 25° C), methanol, DMF (~30 mg/ml), and ethanol (~5 mg/ml). Insoluble in water.
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Safety & Transport Information

Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Entacapone]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Hebei Oxen Special Chemicals Company Limited | Shanghai Eagle Chemical Co., Ltd. | Nanjing King-Pharm Co., Ltd. | Xiang Ding Chemical International Co., Ltd | Nantong Chem-Tech. (Group) Co., Ltd. | Synfine Research Inc. | Hangzhou Hysen Pharma Co., Ltd. | Genatal Life Science Ltd. | Jinan Wedo Industrial Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Jinan Great Chemical Co., Ltd. | Hangzhou Imaginechem Co., Ltd. | Bichem Lab Co., Ltd. | Jinjiangchem Corporation | Zouping Mingxing Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Watson International Ltd | BOC Sciences | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Jinan Haohua Industry Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Beijing Wisdom Chemicals Co., Ltd | Gihi Chemicals Co., Limited | Clearsynth Canada INC. | Nebula Chemicals Co, Ltd. | Yangzhou Princechem Co., Ltd. | Haihang Industry Co., Ltd.

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