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Endothall

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Formula: C8H10O5
CAS: 145-73-3
search Element: endothall
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Identification

Structural Formula
Endothall
CAS:
145-73-3
EINECS:
205-660-5
Molecular Formula:
C8H10O5
MDL:
MFCD01631318
SMILES:
C1CC2C(C(C1O2)C(=O)O)C(=O)O
Synonym:
accelerate ; emdothal ; niagrathal ; endothall ; hydrothol ; hydrothal ; aquathol ; endothal ; hydout ; aquothol


Description

Endothall is a small molecule inhibitor of PP2A (protein phosphatase), used as a defoliant and a known toxin to animals. Endothall shows intermediate inhibition of PP2A (IC50=970 nM), displaying near 50% inhibition of phosphatase activity. The 2,3-dimethyl analogs of Endothall, such as Cantharidin (2,3-dimethyl anhydride analog), approach full inhibition of the phosphatase.


Suppliers

Alfa (A Johnson Matthey Company)
A288864
Santa Cruz Biotechnology, Inc.
201325
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Data is processed


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Properties for Endothall

Molecular Weight:
186.16 g·mol−1
Density:
1.431 g/cm3
Melting point:
179-180°C
Boiling point:
~447.76° C at 760 mmHg (Predicted)
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Safety & Transport Information

Risk Codes:
R21 - Harmful in contact with skin
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T
Hazard symbol T
RID/ADR certification :
UN 2811 6.1 / PG 2
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Alternative Distributors of [Endothall]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Hebei Oxen Special Chemicals Company Limited

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Downloads

Mol File:
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MSDS:
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