Eicosapentaenoyl Serotonin | CAS 199875-71-3

Element: eicosapentaenoyl serotonin

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C-S » Chemicals » eicosapentaenoyl-serotonin-PX86197

Identification

Eicosapentaenoyl Serotonin

CAS:

199875-71-3

EINECS:

Molecular Formula:

C₃₀H₄₀N₂O₂

MDL:

MFCD18428062

SMILES:

CCC=CCC=CCC=CCC=CCC=CCCCC(=O)NCCC1=CNC2=C1C=C(C=C2)O

Synonym:

Description

Eicosapentaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin. Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid-type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain. The effects of replacing the arachidonoyl portion with eicosapentaenoic acid have not been studied. However, replacement of arachidonate with saturated 11- or 12-carbon fatty acids produces compounds that potently inhibit capsaicin-induced TRPV1 channel activation (IC₅₀ = 0.76 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC₅₀ > 50 μM).

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Properties for Eicosapentaenoyl Serotonin

Molecular Weight:

460.66 g·mol−1

Boiling point:

78 °C

Solubility:

Soluble in ethanol (~20 mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml), and ethanol:PBS(pH7.2)(1:2) (~0.33 mg/ml).

Safety & Transport Information

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Alternative Distributors of [Eicosapentaenoyl Serotonin]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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