EGFR/ErbB-2 Inhibitor | CAS 179248-61-4

Element: inhibitor egfr erbb

Page Content Identification Properties Suppliers Prices & Availability Get Quick Quote ☰

Identification Properties Suppliers Prices & Availability Get Quick Quote

C-S » Chemicals » egfr-erbb-inhibitor-PX71149

Identification

EGFR/ErbB-2 Inhibitor

CAS:

179248-61-4

EINECS:

Molecular Formula:

C₂₃H₂₁N₃O₃

MDL:

MFCD08758375

SMILES:

COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OCC4=CC=CC=C4)OC

Synonym:

4-Quinazolinamine, 6,7-dimethoxy-N-[4-(phenylmethoxy)phenyl]-

Description

EGFR/ErbB-2 Inhibitor is a cell-permeable 4-anilino quinazoline compound that acts a potent, reversible, and ATP-competitive inhibitors of EGFR and c-erbB2 (IC₅₀ = 20 nM & 79 nM, respectively), members of the type I growth factor receptor family that is involved in breast cancer development and progression. Shown to effectively inhibit the proliferation (IC₅₀ ~ 1.2-2.5 μM) of tumor cells overexpressing EGRF or Neu (c-erbB-2).

Suppliers

Santa Cruz Biotechnology, Inc.

203935

Get Quick Quote

Prices & Availability

Data is processed

Properties for EGFR/ErbB-2 Inhibitor

Molecular Weight:

387.4 g·mol−1

Density:

1.26 g/cm³ (Predicted)

Melting point:

226.25° C (Predicted)

Boiling point:

560.60° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO, and methanol.

Safety & Transport Information

coming up soon

Alternative Distributors of [EGFR/ErbB-2 Inhibitor]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

Downloads

Mol File:

-/-

MSDS:

-/-