Efavirenz | CAS 154598-52-4 | Chemical-Suppliers

Element: efavirenz

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C-S » Chemicals » efavirenz-PX78846

Identification

Efavirenz

CAS:

154598-52-4

EINECS:

Molecular Formula:

C₁₄H₉ClF₃NO₂

MDL:

MFCD05662344

SMILES:

C1CC1C#C[C@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F

Synonym:

mdp-266 ; l-743726 ; dmp 266 ; efavirenz-d5 ; stocrin ; efavirenz ; efavirenz&int. ; efavuirenz ; efavirnez ; sustiva

Description

Efavirenz is a nonnucleoside HIV-1 reverse transcriptase (RT) inhibitor which selectively inhibits the glucuronidation of 3'-Azido-3'-deoxythymidine β-D-glucuronide, Sodium Salt. Studies suggest that Efavirenz binds to a distinct site of reverse transcriptase which is not the active site. In addition, Efavirenz does not competitively inhibit substrates and template primers, but decreases the enzyme's polymerizing activity. These studies indicate that Efavirenz is also a potent inhibitor of wild-type HIV-1 RT in vitro.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6212484

H&Z Industry Co.,Ltd

HIC180720

Autech Industry Co.,Limited

AIC243972

Chemlyte Solutions

CS162486

Guangzhou Topwork Chemical Co., Ltd.

GTC3241296

Sinogreat Enterprise Ltd.

SE225675

Daming Changda Co., Ltd.

DC216648

CSNpharm, Inc.

CSN10891

Finetech Industry Limited

FIL225900

Pharmacore Co., Limited

PL207621

AK Scientific, Inc.

AS171513

Xingrui Industry Co., Limited

XIL2611044

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

207612

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Prices & Availability

Data is processed

Properties for Efavirenz

Molecular Weight:

315.67 g·mol−1

Density:

1.54 g/cm³ (Predicted)

Melting point:

139-141 °C

Boiling point:

340.56° C at 760 mmHg (Predicted)

Solubility:

Soluble in methanol.

Safety & Transport Information

Risk Codes:

R50 - Very toxic to aquatic organisms

Safety Codes:

S61 - Avoid release to the environment. Refer to special instructions/safety data sheet

Hazard Symbols:

Storage temperature :

-20 °C Freezer

Alternative Distributors of [Efavirenz]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified